4345-49-7

Usage

Chemical structure

1H-Pyrazole ring with two methyl groups (CH3) and a phenyl group (C6H5) attached.

Versatile reactivity

Can react with a variety of other chemicals, making it useful in the synthesis of pharmaceuticals and agrochemicals.

Biological activity

Has been studied for its potential anti-inflammatory, antifungal, and anticancer properties.

Building block for drug discovery

Valuable component in the development of new drugs due to its potential therapeutic properties.

Use in material development

Has potential for use in the development of novel materials.

Precursor in organic synthesis

Can be used as a starting material for the synthesis of other organic compounds.

Upstream product

• 5910-25-8 3-phenylpentane-2,4-dione 
• 75326-06-6 3,5-Dimethyl-3-phenyl-3H-pyrazole 
• 108-86-1 bromobenzene 
• 857530-80-4 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 3398-16-1 4-Bromo-3,5-dimethylpyrazole 
• 98-80-6 phenylboronic acid 
• 705-60-2 1-phenyl-2-nitroprop-1-ene 
• 79-24-3 Nitroethane 
• 103858-98-6 2-(3,5-dimethyl-1⁽²⁾H-pyrazol-4-yl)-aniline 

Downstream Products

• 616879-81-3 ethyl 6-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)nicotinate 
• 59843-47-9 2-(3,5-dimethyl-4-phenyl-pyrazol-1-yl)-N,N-dimethyl-propionamide 

Relevant academic research and scientific papers

Tetravalent metal platinum complex containing tetradentate ligand, preparation method, application and device

The invention relates to the technical field of organic luminescent materials and provides a tetravalent metal platinum complex phosphorescent luminescent material containing a tetradentate ligand. The tetravalent metal platinum complex containing the tetradentate ligand has a structure shown in a first general formula. Meanwhile, the invention also provides a preparation method of the tetravalentmetal platinum complex containing the tetradentate ligand, an application of the tetravalent metal platinum complex containing the tetradentate ligand in an electroluminescent device and a device, the device comprises the tetravalent metal platinum complex containing the tetradentate ligand. According to the tetravalent metal platinum complex containing the tetradentate ligand, the structure of the ligand surrounding the metal center and the structure of the substituent group on the ligand are regulated and controlled to regulate and control the photophysical property of the tetradentate ringmetal platinum complex, and the tetravalent metal platinum complex has the advantage of high stability and has wide application prospect in a plurality of fields such as OLED display, illumination and the like.

Preparation method of pyrazole-4-aryl derivative

The invention discloses a preparation method of a pyrazole-4-aryl derivative. The preparation method comprises the following step: mixing an aryl halide derivative, a pyrazole-4-boronic acid pinacol ester derivative, first alkali, a first phase transfer catalyst and a first palladium-based catalyst in a first solvent to carry out reaction so as to prepare the pyrazole-4-aryl derivative. Through the manner, the pyrazole-4-aryl derivative is prepared through the adoption of a one-pot method; the reaction condition is mild and the post-treatment is simple and convenient, so that the method is suitable for multiple aryl halide derivatives, strong in operability and suitable for industrial production; and the obtained pyrazole compound can be widely applied to the field of chemical engineering,medicines, biology and materials.

Tetradentate cyclometalated platinum complex containing 6-substituted carbazole and preparation method and application thereof

The invention relates to the field of blue phosphorescent tetradentate cyclometalated platinum complexes and discloses a blue phosphorescent tetradentate cyclometalated platinum complex with 6-substituted carbazole and a preparation method and application thereof. The complex herein may be a delayed fluorescent and/or phosphorescent emitter, having the advantages of high thermo-decomposition temperature, great quantum effect, blue emission, narrow emission spectrum and the like; therefore, the complex has a great application prospect in the field of blue light material, particularly the fieldof deep blue phosphorescent materials.

Four-toothed cyclometalated platinum complex with three-substituted pyrazole and preparation method and application

The invention relates to the field of blue light phosphorescence four-toothed cyclometalated platinum complex light emitting materials and discloses a blue light phosphorescence four-toothed cyclometalated platinum complex with three-substituted pyrazole and a preparation method and application. The complex can be a delayed fluorescence and/or phosphorescence emitter, has the characteristics of high thermal decomposition temperatures, great quantum effects, blue light emission, relatively narrow light emission spectrums, and the like, and thus has great application prospects in the field of blue light, particularly dark blue light phosphorescence materials.

Nitrogen-containing heterocycles from metal β-diketonates

Factors determining the reaction of metal β-diketonates with hydrazine, in particular the nature of central metal ion and structure of β-diketonate ligand, are discussed. The possibility for the preparation of other heterocyclic compounds via reaction of metal acetylacetonates with phenylhydrazine, o-phenylenediamine, urea, and thiourea was studied.

HETEROCYCLE FORMATION FROM 1,3-DINITROALKANES. A NOVEL PYRAZOLE SYNTHESIS

1,3-Dinitroalkanes, obtained in almost quantitative yields by Michael additions of nitroalkanes to nitro-olefins, react with hydrazines affording pyrazoles, in most cases in high yields.

MIGRATION TENDENCIES OF FUNCTIONAL GROUPS TOWARD SIGMATROPIC REARRANGEMENT IN 3,3-DISUBSTITUTED 3H-PYRAZOLES

3,3-Disubstituted 3H-pyrazoles la - e aromatise through an intramolecular sigmatropic 1,5-(1,2-)shift of one of the quaternary groups.From a kinetic study of the uncatalysed and of the acid catalysed isomerisation reaction migration tendencies of functional groups in sigmatropic rearrangement toward neutral and toward cationic centers are obtained.