4354-61-4

Basic information

• Product Name: 3-cyclohexyl-3-hydroxypropanamide
• Synonyms: 3-cyclohexyl-3-hydroxypropanamide
• CAS NO: 4354-61-4
• Molecular Weight: 171.239
• Mol File: 4354-61-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-cyclohexyl-3-hydroxypropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-cyclohexyl-3-hydroxypropanamide(4354-61-4)
• EPA Substance Registry System: 3-cyclohexyl-3-hydroxypropanamide(4354-61-4)

Safety Data

• Hazardous Substances Data: 4354-61-4(Hazardous Substances Data)

Upstream product

• 126678-67-9 rac-3-cyclohexyl-3-hydroxypropionitrile 
• 2043-61-0 cyclohexanecarbaldehyde 
• 62455-70-3 3-cyclohexyl-3-oxopropanenitrile 

Relevant articles and documents

Selective transformation of nitriles into amides and carboxylic acids by an immobilized nitrilase

Using an immobilized nitrilase from Rhodococcus sp. mild and selective hydrolysis of nitriles can be achieved even in the presence of acid or base sensitive groups under neutral conditions. This method is applicable to a broad range of substrates as exemplified by aliphatic, alicyclic, heterocyclic and carbohydrate type nitriles.

One-pot nitrile aldolization/hydration operation giving β-hydroxy carboxamides

Rhodium to the rescue: The formal aldol products of carboxamides (CONH 2) were obtained by using a RhI(OR) (R=H, Me) catalyst under essentially neutral pH and ambient conditions. This novel aldol strategy is based on the catalytic al