126678-67-9Relevant articles and documents
A robust nickel catalyst for cyanomethylation of aldehydes: Activation of acetonitrile under base-free conditions
Chakraborty, Sumit,Patel, Yogi J.,Krause, Jeanette A.,Guan, Hairong
supporting information, p. 7523 - 7526 (2013/07/26)
Nick of time: The nickel cyanomethyl complex 1 catalyzes the room temperature coupling of aldehydes with acetonitrile under base-free conditions. The catalytic system is long-lived and remarkably efficient with high turnover numbers (TONs) and turnover fr
One-pot nitrile aldolization/hydration operation giving β-hydroxy carboxamides
Goto, Akihiro,Naka, Hiroshi,Noyori, Ryoji,Saito, Susumu
supporting information; experimental part, p. 1740 - 1743 (2011/12/16)
Rhodium to the rescue: The formal aldol products of carboxamides (CONH 2) were obtained by using a RhI(OR) (R=H, Me) catalyst under essentially neutral pH and ambient conditions. This novel aldol strategy is based on the catalytic al
P(i-PrNCH2CH2)3N as a Lewis base catalyst for the synthesis of β-hydroxynitriles using TMSAN
Wadhwa, Kuldeep,Verkade, John G.
experimental part, p. 5683 - 5686 (2009/12/06)
(Equation Presented) Proazaphosphatrane 1a was found to be an efficient catalyst for synthesis of β-hydroxynitriles via the reaction of trimethylsilylacetonitrile (TMSAN) with aldehydes under mild reaction conditions and typically low catalyst loading (ca. 2 mol %). A variety of functional groups were tolerated, and good to excellent product yields were obtained.
