4355-47-9

Upstream product

• 1823-91-2 1-phenylethyl cyanide 
• 109-65-9 1-bromo-butane 
• 53310-47-7 α-Ethylthio-α-phenyl-propionitril 
• 106-99-0 buta-1,3-diene 
• 60340-31-0 Ethylsulfanyl-phenyl-acetonitrile 

Relevant academic research and scientific papers

Transition metal-free addition of ketones or nitriles to 1,3-dienes

The simpler the better (or going green): The first examples of the catalytic addition of 1,3-dienes to simple ketones or nitriles are described. These reactions can be effected on a kilogram scale, representing the shortest access featuring a perfect atom economy to molecules of interest in the perfume industry. The Royal Society of Chemistry.

THE REDUCTIVE LITHIATION OF THIOACETALS, α,α-BIS(TRIMETHYLSILYL)-ALKYL SULFIDES, AND 2-ALKYL-2-ETHYLTHIOALKANENITRILES USING TRIBUTYLSTANNYLLITHIUM

The reaction of thioacetals of phenyl ketones, α,α-bis(trimethylsilyl)alkyl sulfides, and 2-alkyl-2-ethylthioalkanenitriles with tributhylstannyllithium gave the corresponding α-anions of sulfides, α,α-bis(trimethylsilyl)alkane, and nitriles, respectively.