436159-73-8Relevant academic research and scientific papers
Substrate-dependent nonlinear effects in proline-thiourea-catalyzed aldol reactions: Unraveling the role of the thiourea co-catalyst
Ei-Hamdouni, Niama,Companyo, Xavier,Rios, Ramon,Moyano, Albert
, p. 1142 - 1148 (2010)
Figure Presented It's an affair of four: The study of nonlinear effects in the proline-thioureacatalyzed aldol reaction between acetone and aromatic aldehydes, together with NMR and ESI-MS experiments, shows that the main role of the thiourea co-catalyst is that of promoting both the formation of a soluble Seebach's oxazolidinone intermediate and its conversion into the iminium carboxylate isomer.
