436800-48-5Relevant academic research and scientific papers
Nickel-catalyzed amination of aryl sulfamates
Ramgren, Stephen D.,Silberstein, Amanda L.,Yang, Yang,Garg, Neil K.
, p. 2171 - 2173 (2011)
Broad in scope: The first amination of aryl sulfamates, which are attractive cross-coupling partners, particularly for multistep syntheses, was achieved by using a nickel catalyst. The method provides a versatile means to use simple derivatives of phenol as precursors to polysubstituted aryl amines, as exemplified by a concise synthesis of the antibacterial drug linezolid (see scheme).
AMINATION OF ARYL ALCOHOL DERIVATIVES
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Page/Page column 47; 54, (2012/07/27)
Embodiments of the invention provide methods and materials for chemical cross-coupling reactions that utilize aryl alcohol derivatives as cross-coupling partners. Embodiments of the invention include methods for the amination of aryl sulfamates and carbamates, which are attractive cross-coupling partners, particularly for use in multistep synthesis. Illustrative embodiments include versatile means to use simple derivatives of phenol as precursors to polysubstituted aryl amines, as exemplified by a concise synthesis of the antibacterial drug linezolid.
Nickel-catalyzed amination of aryl sulfamates and carbamates using an air-stable precatalyst
Hie, Liana,Ramgren, Stephen D.,Mesganaw, Tehetena,Garg, Neil K.
supporting information; experimental part, p. 4182 - 4185 (2012/09/25)
A facile nickel-catalyzed method to achieve the amination of synthetically useful aryl sulfamates and carbamates is reported. Contrary to most Ni-catalyzed amination reactions, this user-friendly approach relies on an air-stable Ni(II) precatalyst, which, when employed with a mild reducing agent, efficiently delivers aminated products in good to excellent yields. The scope of the method is broad with respect to both coupling partners and includes heterocyclic substrates.
Light-emitting carbazole derivatives: Potential electroluminescent materials
Justin Thomas,Lin,Tao,Ko
, p. 9404 - 9411 (2007/10/03)
Stable carbazole derivatives that contain peripheral diarylamines at the 3- and 6-positions and an ethyl or aryl substituent at the 9-position of the carbazole moiety have been synthesized via palladium-catalyzed C-N bond formation. These new carbazole compounds (carbs) are amorphous with high glass transition temperatures (Tg, 120-194°C) and high thermal decomposition temperatures (Td > 450°C). The compounds are weakly to moderately luminescent in nature. The emission wavelength ranges from green to blue and is dependent on the substituent at the peripheral nitrogen atoms. Two types of light-emitting diodes were constructed from carb: (I) ITO/carb/TPBI/Mg:Ag and (II) ITO/carb/Alq3/Mg:Ag, where TPBI and Alq3 are 1,3,5-tris(N-phenylbenzimidazol-2-yl)benzene and tris(8-hydroxyquinoline) aluminum, respectively. In type I devices, the carb functions as the hole-transporting as well as emitting material. In type II devices, either carb, or Alq3 is the light-emitting material. Several green light-emitting devices exhibit exceptional maximum brightness, and the physical performance appears to be better than those of typical green light-emitting devices of the structure ITO/diamine/Alq3/Mg:Ag. The relation between the LUMO of the carb and the performance of the light-emitting diode is discussed.
