436801-01-3Relevant academic research and scientific papers
Sequenced reactions with samarium(II) iodide. Sequential intramolecular Reformatsky/nucleophilic acyl substitution reactions for the synthesis of medium-sized carbocycles
Molander, Gary A.,Brown, Giles A.,De Gracia, Isabel Storch
, p. 3459 - 3463 (2002)
Samarium(II) iodide was used to access eight- and nine-membered carbocycles via a domino reaction comprised of a Reformatsky reaction followed by a nucleophilic acyl substitution reaction. This method represents a general and efficient approach to a variety of highly functionalized, stereodefined carbocycles.
