4370-81-4

Upstream product

• 24131-01-9 2,2,5-trimethyl-5-phenyl-1,3-dioxane-4,6-dione 
• 114467-55-9 2-methyl-2-phenylbut-3-en-1-ol 
• 16141-26-7 ethyl 3-hydroxy-2-methyl-2-phenylpropanoate 
• 50-00-0 formaldehyd 
• 492-37-5 hydratropic acid 
• 201230-82-2 carbon monoxide 
• 6006-81-1 3-hydroxy-2-phenylpropene 

Downstream Products

• 16141-26-7 ethyl 3-hydroxy-2-methyl-2-phenylpropanoate 
• 27219-72-3 2-phenyl-2-(chloromethyl)propanoyl chloride 
• 129779-99-3 2-(diethylamino)ethyl α-methyltropate 
• 69956-49-6 3-Benzyloxy-5,6-dihydro-5-methyl-5-phenyl-2H-1,3-oxazin-2,4(3H)-dion 
• 69956-48-5 3-(3-chloro-phenyl)-5-methyl-5-phenyl-[1,3]oxazinane-2,4-dione 
• 81467-31-4 5,6-Dihydro-3-hydroxy-5-methyl-5-phenyl-2H-1,3-oxazin-2,4-(3H)-dion 
• 81467-30-3 3-(2-Hydroxy-1-methyl-1-phenylethyl)-1,4,2-dioxazol-5-on 
• 129808-98-6 2-(diethylamino)ethyl 2-methyl-2-phenyl-3-(tosyloxy)propanoate 
• 129780-03-6 3-Iodo-2-methyl-2-phenyl-propionic acid 2-diethylamino-ethyl ester 
• 129780-02-5 3-Bromo-2-methyl-2-phenyl-propionic acid 2-diethylamino-ethyl ester 
• 129780-01-4 2-(diethylamino)ethyl 2-methyl-2-phenyl-3-chloropropanoate 
• 129780-00-3 2-(diethylamino)ethyl 3-fluoro-2-methyl-2-phenylpropanoate 
• 129779-98-2 3-acetoxy-2-methyl-2-phenyl-propionic acid-(2-diethylamino-ethyl ester) 
• 69956-43-0 N-benzyloxy-3-hydroxy-2-methyl-2-phenyl-propionamide 

Relevant academic research and scientific papers

Mechanistic investigation of the selective reduction of Meldrum's acids to β-hydroxy acids using SmI2 and H2O

The mechanism of a recently reported first mono-reduction of cyclic 1,3-diesters (Meldrum's acids) to β-hydroxy acids with SmI 2-H2O has been studied using a combination of reactivity, deuteration, kinetic isotope and radical clock e

Synthesis of quaternary carbon centers via hydroformylation

The application of hydroformylation to the synthesis of quaternary carbon centers is reported. The synthesis of the highly substituted carbon is achieved by applying a catalytic amount of 1. Ligand 1 serves as a catalytic directing group by covalently and reversibly binding to both the substrate and catalyst. The intramolecular nature of the directing group strategy accelerates the hydroformylation reaction such that the reaction is performed at mild temperatures (35-55 °C) and with excellent regioselectivity (b:l > 94:6).

Nickel-catalyzed highly selective hydrovinylation of α-ketals of vinylarenes

A nickel-catalyzed hydrovinylation of α-ketal derivatives of vinylarenes has been developed, providing a new method for preparing functional olefins with a quarternary carbon center in high yields and selectivities.

Molecular Modification of Anticholinergics as Probes for Muscarinic Receptors. 2. Amino Esters of α-Methyltropic Acid

As a continuation of our goals to study molecular probes for muscarinic cholinergic receptors, a series of 3-substituted 2-methyl-2-phenylpropanoates with the general structure C6H5C(CH2X)CH3)COOCH2CH2NEt2 where X=OH, OTs, F, Cl, Br, I, and OAc were prepa