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437655-89-5

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437655-89-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 437655-89-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,7,6,5 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 437655-89:
(8*4)+(7*3)+(6*7)+(5*6)+(4*5)+(3*5)+(2*8)+(1*9)=185
185 % 10 = 5
So 437655-89-5 is a valid CAS Registry Number.

437655-89-5Relevant articles and documents

Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]-amino]-5-oxazolyl]phenyl]-N- methyl-4-morpholinea0cetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activity

Dhar, T.G. Murali,Shen, Zhongqi,Guo, Junqing,Liu, Chunjian,Watterson, Scott H.,Gu, Henry H.,Pitts, William J.,Fleener, Catherine A.,Rouleau, Katherine A.,Sherbina,McIntyre, Kim W.,Witmer, Mark R.,Tredup, Jeffrey A.,Chen, Bang-Chi,Zhao, Rulin,Bednarz, Mark S.,Cheney, Daniel L.,MacMaster, John F.,Miller, Laura M.,Berry, Karen K.,Harper, Timothy W.,Barrish, Joel C.,Hollenbaugh, Diane L.,Iwanowicz, Edwin J.

, p. 2127 - 2130 (2007/10/03)

Inosine monophosphate dehydrogenase (IMPDH) is a key enzyme that is involved in the de novo synthesis of purine nucleotides. Novel 2-aminooxazoles were synthesized and tested for inhibition of IMPDH catalytic activity. Multiple analogues based on this che

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