4380-83-0

Basic information

• Product Name: N-(piperidin-1-ylmethyl)benzamide
• Synonyms: Benzamide, N-(1-piperidinylmethyl)-
• CAS NO: 4380-83-0
• Molecular Formula: C₁₃H₁₈N₂O
• Molecular Weight: 218.2948
• Mol File: 4380-83-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 400.9°C at 760 mmHg
• Flash Point: 196.2°C
• Density: 1.073g/cm³
• Vapor Pressure: 1.23E-06mmHg at 25°C
• Refractive Index: 1.547
• CAS DataBase Reference: N-(piperidin-1-ylmethyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(piperidin-1-ylmethyl)benzamide(4380-83-0)
• EPA Substance Registry System: N-(piperidin-1-ylmethyl)benzamide(4380-83-0)

Safety Data

• Hazardous Substances Data: 4380-83-0(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 6282-02-6 N-(hydroxymethyl)benzamide 
• 56-23-5 tetrachloromethane 
• 53497-62-4 N-piperidinomethyl-benzenesulfonamide 
• 55-21-0 benzamide 
• 50-00-0 formaldehyd 
• 59917-58-7 N-(Dimethylaminomethyl)benzamide 
• 38792-42-6 N-(chloromethyl)benzamide 

Downstream Products

• 51643-77-7 benzamidomethyl benzyl sulphide 
• 110-89-4 piperidine 
• 50-00-0 formaldehyd 
• 55-21-0 benzamide 

Relevant articles and documents

[Omim][Bf4] ionic liquid, a green and recyclable medium for one-pot aminomethylation of electron-rich aromatic compounds

An efficient catalyst-free procedure has been developed for one-pot aminomethylation of some electron-rich aromatic compounds such as 1- and 2-naphthols, indole, N-methylindol and benzamide, in [omim][BF4] ionic liquid at room temperature. The ionic liquid can be recovered and reused without any noticeable loss of performance.

Solvent-free preparation of monoacylaminals assisted by microwave irradiation

Reaction of amide 1, aldehyde 2, and amine 3 promoted by microwave irradiation produced monoacylaminals 4 up to 100% yield in a short time under solvent-free conditions.