Benzamide, N-(1-piperidinylmethyl)-

Base Information

• Chemical Name: Benzamide, N-(1-piperidinylmethyl)-
• CAS No.: 4380-83-0
• Molecular Formula: C13H18N2O
• Molecular Weight: 218.299
• NSC Number: 342668
• UNII: 8BM3QBY7GU
• DSSTox Substance ID: DTXSID30963119
• Nikkaji Number: J1.369.810D
• Wikidata: Q82944929
• Mol file: 4380-83-0.mol

Synonyms:Benzamide, N-(1-piperidinylmethyl)-;8BM3QBY7GU;N-(1-Piperidinylmethyl)benzamide;NSC-342668;N-(Piperidinomethyl)benzamide;N-(piperidin-1-ylmethyl)benzamide;piperidinomethyl benzamide;UNII-8BM3QBY7GU;SCHEMBL3174309;DTXSID30963119;N-Piperidin-1-ylmethyl-benzamide;ATCWBLHLEMDUCP-UHFFFAOYSA-N;NSC342668;NSC 342668;N-[(Piperidin-1-yl)methyl]benzenecarboximidic acid

Chemical Property of Benzamide, N-(1-piperidinylmethyl)-

Chemical Property:

• Vapor Pressure: 1.23E-06mmHg at 25°C
• Boiling Point: 400.9°C at 760 mmHg
• Flash Point: 196.2°C
• Density: 1.073g/cm³
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 218.141913202
• Heavy Atom Count: 16
• Complexity: 218

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCN(CC1)CNC(=O)C2=CC=CC=C2

Technology Process of Benzamide, N-(1-piperidinylmethyl)-

There total 10 articles about Benzamide, N-(1-piperidinylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

piperidine (110-89-4) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + benzamide (55-21-0,27208-38-4) → N-(piperidinomethyl)benzamide (4380-83-0)

Guidance literature:

With 1-octyl-3-methylimidazolium tetrafluoroborate; at 20 ℃; for 4h;

DOI:10.3184/174751913X13635476751996

Reference yield:

tetrachloromethane (56-23-5) + N-piperidinomethyl-benzenesulfonamide (53497-62-4) + benzamide (55-21-0,27208-38-4) → benzenesulfonamide (98-10-2) + N-(piperidinomethyl)benzamide (4380-83-0) + N-(benzenesulfonylamino-methyl)-benzamide (100870-71-1)

Guidance literature:

Erhitzen;

Reference yield:

benzamide (55-21-0,27208-38-4) → N-(piperidinomethyl)benzamide (4380-83-0)

Guidance literature:

Multi-step reaction with 2 steps

1: diluted sulfuric acid

With sulfuric acid;

upstream raw materials:

piperidine

N-(hydroxymethyl)benzamide

N-(chloromethyl)benzamide

N-(Dimethylaminomethyl)benzamide

Downstream raw materials:

piperidine

formaldehyd

benzamide

benzamidomethyl benzyl sulphide

Refernces

• 1、 Singh, Balgar,Mahajan, Simpy,Sheikh,Sharma, Mohita,Kalsotra, Bansi Lal. "Peroxo complexes of uranium(VI) containing nitrogen and oxygen donor ligands1". body text. p. 1079 - 1088. Retrieved 2012/10/08.