4380-99-8

Upstream product

• 4381-01-5 1,2-bis(3-cyanophenyl)ethane 
• 591-17-3 meta-bromotoluene 
• 823-78-9 meta-bromobenzyl bromide 
• 82732-03-4 1,1'-(1,2-ethanediyl)bis-3-bromobenzene 
• 120-33-2 ethyl 3-methylbenzoate 
• 62290-17-9 ethyl 3-bromomethylbenzoate 

Downstream Products

• 96841-94-0 1,2-bis(m-methoxycarbonylphenyl)ethane 
• 121262-86-0 1,2-Bis<3-(brommethyl)phenyl>ethan 
• 108843-01-2 3,3'-bis(hydroxymethyl)diphenylethane 
• 390358-54-0 1,2-bis{3-[(6-amino-2-pyridyl)carbamoyl]phenyl}ethane 

Relevant academic research and scientific papers

Molecular recognition of xanthine alkaloids: First synthetic receptors for theobromine and a series of new receptors for caffeine

Synthetic receptors and a series of new receptors were designed and synthesized for theobromine, a xanthine alkaloid used as a diuretic. The binding results of the theobromine and caffeine were also studied using NMR and UV methods. It was observed that the synthesis of the receptor H6 is achieved by Co(PPh3)3Cl-mediated homocoupling of 3-(ethoxycarbonyl)benzyl bromide 12 under mild conditions.

Troger's base molecular scaffolds in dicarboxylic acid recognition

Artificial receptors (1-5) have been designed and synthesized from simple precursors. The chain length selectivity studies of dicarboxylic acids within the cavities of new fluorescent Troger's base molecular frameworks (1- 3) have been carried out with a critical examination of their role of rigidity as well as flexibility in selective binding in comparison to receptor 5. The chiral resolution of the racemic Troger's base receptors (1 and 2) by chiral recognition with (+)- camphoric acid using hydrogen-bonding interactions has been studied.