439291-57-3Relevant articles and documents
Dual role of ethyl bromodifluoroacetate in the formation of fluorine-containing heteroaromatic compounds
Ma, Xingxing,Mai, Shaoyu,Zhou, Yao,Cheng, Gui-Juan,Song, Qiuling
, p. 8960 - 8963 (2018)
An efficient one-pot cascade process via unprecedented quadruple cleavage of BrCF2COOEt with primary amines to afford valuable fluorine-containing heterocycles is described, in which BrCF2COOEt plays a dual role as a C1 synthon and a difluoroalkylating reagent for the first time. Mechanistic studies supported by DFT calculations suggest that a base plays an active role in the formation of the key intermediate isocyanides generated in situ from primary amines and difluorocarbene.
Sodium Sulfite-Involved Photocatalytic Radical Cascade Cyclization of 2-Isocyanoaryl Thioethers: Access to 2-CF2/CF3-Containing Benzothiazoles
Yuan, Yao,Dong, Wuheng,Gao, Xiaoshuang,Xie, Xiaomin,Zhang, Zhaoguo
supporting information, p. 469 - 472 (2019/01/11)
A visible-light-induced radical cascade cyclization of 2-isocyanoaryl thioethers for the synthesis of 2-CF2/CF3-containing benzothiazoles has been developed. Sodium sulfite can participate in the photocatalytic cycle as a reductant that efficiently transforms Ir4+ into Ir3+ to promote the fluoroalkylation under mild reaction conditions.
Visible light photocatalytic synthesis of benzothiophenes
Hari, Durga Prasad,Hering, Thea,Koenig, Burkhard
, p. 5334 - 5337,4 (2012/12/12)
The photocatalytic reaction of o-methylthio-arenediazonium salts with alkynes yields substituted benzothiophenes regioselectively through a radical annulation process. Green light irradiation of eosin Y initiates the photoredox catalysis. The scope of the reaction was investigated by using various substituted diazonium salts and different alkynes.
