439683-93-9

Upstream product

• 100-39-0 benzyl bromide 
• 310870-34-9 2-azido-4,6-O-benzylidene-2-deoxy-1-thio-D-glucopyranoside 
• 183875-22-1 phenyl 2-azido-2-deoxy-3,4,6-tri-O-acetyl-1-thio-α/β-D-glucopyranoside 
• 202462-37-1 phenyl 2-azido-2-deoxy-1-thio-α/β-D-glucopyranoside 
• 171032-74-9 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-D-glucopyranose 
• 1078691-95-8 (+)-D-glucosamine hydrochloride 

Downstream Products

• 367518-26-1 trichloroacetoimidoyl 4-O-acetyl-2-azido-3,6-di-O-benzyl-2-deoxy-α/β-D-glucopyranoside 
• 310870-32-7 Acetic acid (2R,3S,4R,5R)-5-azido-4-benzyloxy-2-benzyloxymethyl-6-phenylsulfanyl-tetrahydro-pyran-3-yl ester 
• 310870-37-2 O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α,β-D-glucopyranosyl) trichloroacetimidate 
• 918868-69-6 toluene-4-sulfonic acid 5-azido-4-benzyloxy-3-hydroxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl ester 
• 918868-75-4 acetic acid 5-azido-2-azidomethyl-4-benzyloxy-6-phenylsulfanyl-tetrahydro-pyran-3-yl ester 
• 918868-71-0 5-azido-2-azidomethyl-4-benzyloxy-6-phenylsulfanyl-tetrahydro-pyran-3-ol 
• 918868-67-4 5-azido-4-benzyloxy-2-hydroxymethyl-6-phenylsulfanyl-tetrahydro-pyran-3-ol 
• 439683-95-1 phenyl 2-azido-3,6-di-O-benzyl-2-deoxy-1-thio-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of aminoglycoside derivatives on a Cbz-type heavy fluorous tag

Four aminoglycoside derivatives containing a 2,6-diamino-2,6-dideoxy-d-glucopyranose disaccharide structure were successfully prepared by using a Cbz-type heavy fluorous tag in a fluorous synthesis. A Cbz-type heavy fluorous tag was prepared using the hex

Inositolphosphoglycan mediators structurally related to glycosyl phosphatidylinositol anchors: Synthesis, structure and biological activity

The preparation of the pseudopentasaccharide 1a, an inositolphosphoglycan (IPG) that contains the conserved linear structure of glycosyl phosphatidylinositol anchors (GPI anchors), was carried out by using a highly convergent 2+3-block synthesis approach which involves imidate and sulfoxide glycosylation reactions. The preferred solution conformation of this structure was determined by using NMR spectroscopy and molecular dynamics simulations prior to carrying out quantitative structure-activity relationship studies in connection with the insulin signalling process. The ability of 1a to stimulate lipogenesis in rat adipocites as well as to inhibit cAMP dependent protein kinase and to activate pyruvate dehydrogenase phosphatase was investigated. Compound 1a did not show any significant activity, which may be taken as a strong indication that the GPI anchors are not the precursors of the IPG mediators.