440084-59-3Relevant academic research and scientific papers
Use of a sterically demanding Lewis acid to direct ring expansion of monoactivated methylenecyclopropanes
Taillier, Catherine,Bethuel, Yann,Lautens, Mark
, p. 8469 - 8477 (2007)
A novel synthetic route for the preparation of functionalized alkylidene pyrrolidines via a MAD/n-Bu4NI-mediated ring expansion of monoactivated MCP was developed. The substrate scope for this reaction was found to be broad for a variety of ald
Divergent selectivity in Mgl2-mediated ring expansions of methylenecyclopropyl amides and imides
Lautens, Mark,Han, Wooseok
, p. 6312 - 6316 (2007/10/03)
We report a novel approach to prepare five- and six-membered heterocyclic compounds via a ring expansion of monoactivated methylenecyclopropanes (MCPs) with aldimines and aldehydes in the presence of MgI2. Monoactivated MCPs behave as homo-Mich
