440111-10-4

Usage

Uses

Used in Organic Chemistry:
(4-iodophenyl)diphenyl-Phosphine is used as a ligand in organic chemistry for its ability to form coordination complexes with various metal ions. This enhances the reactivity and selectivity of the metal centers, facilitating a wide range of chemical reactions.
Used in Coordination Chemistry:
In coordination chemistry, (4-iodophenyl)diphenyl-Phosphine is used as a ligand to create stable and well-defined coordination complexes. These complexes are essential in understanding the structure and properties of metal-ligand interactions, as well as their potential applications in catalysis and materials science.
Used in Pharmaceutical Compound Synthesis:
(4-iodophenyl)diphenyl-Phosphine is used as a valuable intermediate in the synthesis of organic and pharmaceutical compounds. Its unique structure and reactivity make it a useful building block for the development of new drugs and therapeutic agents.
Used in Cross-Coupling Reactions:
(4-iodophenyl)diphenyl-Phosphine is employed as a reactant in cross-coupling reactions, which are crucial for the formation of carbon-carbon and carbon-heteroatom bonds in organic synthesis. These reactions are widely used in the preparation of complex molecular structures, including those found in pharmaceuticals and advanced materials.
Used in Palladium-Catalyzed Coupling Reactions:
This phosphine derivative is also used in palladium-catalyzed coupling reactions, which are essential for the formation of carbon-carbon bonds in various organic compounds. These reactions are widely utilized in the synthesis of complex organic molecules, including those with potential applications in the pharmaceutical and chemical industries.

Upstream product

• 624-38-4 para-diiodobenzene 
• 829-85-6 diphenylphosphane 
• 734-59-8 (4-bromophenyl)diphenylphosphane 
• 591-50-4 iodobenzene 
• 1079-66-9 chloro-diphenylphosphine 

Downstream Products

• 1558928-67-8 (4-(bromomethyl)benzyl)(4-iodophenyl)diphenylphosphonium bromide 

Relevant academic research and scientific papers

High mitochondrial accumulation of new gadolinium(III) agents within tumour cells

The first bifunctional GdIII complexes covalently bound to arylphosphonium cations and the first tumour-cell selective mitochondrial agents designed for potential application in binary cancer therapies are reported. The highest in vitro cellula

Photoswitchable electrochemical behaviour of a [FeFe] hydrogenase model with a dithienylethene derivative

A diiron dithiolate complex 1o with a dithienylethene (DTE) phosphine ligand has been elaborately designed and fully investigated by spectroscopic and DFT computational studies. Upon irradiation with UV light, the DTE moiety in complex 1o undergoes an exc

Water soluble phosphines Part XV. Syntheses of multiply functionalized and chiral phospine ligands by Pd-catalyzed P-C and C-C coupling reactions

Phosphine ligands containing mono- and multiply substituted aromatic substituents (1-13, 19a and 19b) are accessible in high yields by palladium-catalyzed P-C coupling reactions between primary, secondary or disecondary phosphines and iodo- or bromoaromatic compounds. The reaction is of broad applicability and compatible with electron donor or electron acceptor substituents in ortho, meta or para position to the halogen in the aromatic ring systems. It may be performed in protic and aprotic solvents. The chiral spirocyclic boronato complex 15a is formed upon reaction of 3 with boric acid, while with benzeneboronic acid 15c with a peripheral Lewis acid group is obtained. The Pd-mediated P-C coupling reaction of primary phosphines proceeds stepwise, tailor-made chiral secondary (16) and tertiary phosphines (17) being formed in high yield. Through combination with Suzuki-type C-C coupling reactions, the scope of Pd-catalyzed P-C coupling may be extended further, novel ligands (20a, 20b, 21a, 21b) with biphenylyl substituents being accessible. The X-ray structures of the salicylic acid derivative 3 (space group P1) and of ortho-iso-propylphenyl-diphenylphosphine 6 (space group Pbca) have been determined.