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3-Bromo-5-chloropyrazine-2-carbonitrile is a chemical compound with the molecular formula C5HBrClN3. It is composed of multiple elements, including bromine, chlorine, carbon, nitrogen, and hydrogen. 3-Bromo-5-chloropyrazine-2-carbonitrile belongs to the class of organic compounds known as pyrazines, which are polycyclic aromatic compounds containing a pyrazine ring. The pyrazine ring is a six-membered aromatic heterocycle made up of two nitrogen atoms and four carbon atoms. It is used as a reagent in organic synthesis, and its properties may vary depending on factors such as temperature, pressure, concentration, and pH. Due to its potential reactiveness or toxicity, it should be handled with care.

440124-25-4

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440124-25-4 Usage

Uses

Used in Organic Synthesis:
3-Bromo-5-chloropyrazine-2-carbonitrile is used as a reagent in organic synthesis for its unique chemical properties. It can be employed in the preparation of various organic compounds, contributing to the development of new materials and pharmaceuticals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Bromo-5-chloropyrazine-2-carbonitrile is used as a building block for the synthesis of potential drug candidates. Its structural features allow for the creation of molecules with specific biological activities, making it a valuable component in the development of new therapeutic agents.
Used in Chemical Research:
3-Bromo-5-chloropyrazine-2-carbonitrile is also used in chemical research as a model compound to study the properties and reactivity of pyrazine derivatives. This helps researchers understand the behavior of similar compounds and develop new synthetic strategies and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 440124-25-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,0,1,2 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 440124-25:
(8*4)+(7*4)+(6*0)+(5*1)+(4*2)+(3*4)+(2*2)+(1*5)=94
94 % 10 = 4
So 440124-25-4 is a valid CAS Registry Number.
InChI:InChI=1/C5HBrClN3/c6-5-3(1-8)9-2-4(7)10-5/h2H

440124-25-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Bromo-5-chloropyrazine-2-carbonitrile

1.2 Other means of identification

Product number -
Other names Pyrazinecarbonitrile,3-bromo-5-chloro-(9CI)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:440124-25-4 SDS

440124-25-4Downstream Products

440124-25-4Relevant academic research and scientific papers

Discovery of pyrazol-3-ylamino pyrazines as novel JAK2 inhibitors

Ioannidis, Stephanos,Lamb, Michelle L.,Davies, Audrey M.,Almeida, Lynsie,Su, Mei,Bebernitz, Geraldine,Ye, Minwei,Bell, Kirsten,Alimzhanov, Marat,Zinda, Michael

scheme or table, p. 6524 - 6528 (2010/05/18)

The design, synthesis and biological evaluation of a series of pyrazol-3-ylamino pyrazines as potent and selective JAK2 kinase inhibitors is reported, along with the pharmacokinetic and pharmacodynamic properties of lead compounds.

PYRAZOLYL-AMINO-SUBSTITUTED PYRAZINES AND THEIR USE FOR THE TREATMENT OF CANCER

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Page/Page column 71, (2008/12/04)

The present invention relates to compounds of Formula (I): and to their pharmaceutical compositions, and to their methods of use. These novel compounds provide a treatment for myeloproliferative disorders and cancer.

Pyrimidine, pyrazine and triazine derivatives

-

, (2008/06/13)

The present invention is a pyrimidine, triazine or pyrazine derivative of the formula or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, R4, X, Y and Z are as defined in the specification. The invention is a pharmaceutical composition containing an effective amount of the compound of formula 1, its preparation and to a method of treatment, control or prevention of acute and/or chronic neurological disorders by administering a therapeutically effective amount of a compound of formula 1.

Pyrazine and triazine derivatives of 1,2,4,5-tetrahydro-Benzo or Thieno [d] azepine

-

, (2008/06/13)

The invention relates to compounds which are represented by the formula wherein R1, R2, R3, R4, X and Y are as defined in the specification, as well as pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing these compounds and to a process for their preparation. The compounds possess affinity towards metabotropic glutamate receptors and are therefore useful in the treatment or prevention of acute and/or chronic neurological disorders.

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