4402-18-0Relevant academic research and scientific papers
Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database and chemical similarity searching
Parkesh, Raman,Childs-Disney, Jessica L.,Nakamori, Masayuki,Kumar, Amit,Wang, Eric,Wang, Thomas,Hoskins, Jason,Tran, Tuan,Housman, David,Thornton, Charles A.,Disney, Matthew D.
, p. 4731 - 4742 (2012)
Myotonic dystrophy type 1 (DM1) is a triplet repeating disorder caused by expanded CTG repeats in the 3'-untranslated region of the dystrophia myotonica protein kinase (DMPK) gene. The transcribed repeats fold into an RNA hairpin with multiple copies of a
