4403-08-1Relevant academic research and scientific papers
Development and characterization of triazine based dendrimers for delivery of antitumor agent
Bansal, Kuldeep K.,Kakde, Deepak,Gupta, Umesh,Jain, Narendra K.
, p. 8395 - 8404 (2010)
In the present study we developed the novel kind of triazine dendrimers by utilizing differential reactivity of the cyanuric chloride (triazine trichloride) which overcome the limitations associated with the others classes of dendrimers like toxicity, low yield, high synthesis cost etc. Triazine dendrimers were synthesized by divergent method using triazine trichloride as core and diethanolamine as branching unit to avoid the use of protecting group and functional group interconversion up to third generation. These hydroxyl terminated dendrimers were characterized by FTIR, 1HNMR, 13CNMR, ES mass spectroscopy, and by Elemental analysis. The yield of pure G3 dendrimers was 63%. This novel dendrimers increases the aqueous solubility of hydrophobic drug Paclitaxel up to 0.562 mg/ml as well as showed control release behavior. Hemolytic and toxicology studies of this dendrimer in mice showed no adverse toxicity to the kidneys and the liver up to 200 mg/kg dose (i.p). Triazine being a hydrophobic compound, the core of this dendrimer is hydrophobic and supposed to easily incorporate the hydrophobic guest while presence of hydroxyl group on periphery increases its water solubility and reduces its toxicity; and thus it is useful in various fields like gene delivery, MRI contrasting agents, vaccines or as solubilization tool. Copyright
NOVEL TRIAZINE COMPOUND, ALL-SOLID-STATE POLYMER ELECTROLYTE COMPOSITION AND USE THEREOF
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Paragraph 0220-0223, (2018/04/12)
The present invention relates to a novel triazine compound represented by chemical formula 1, an all-solid-state polymer electrolyte composition comprising the same as a cross-linking agent and uses thereof. More specifically, the triazine compound effectively inhibits crystallization of a plasticizer at a low temperature (room temperature) to show significantly improved ion conductivity, and can realize significantly improved electrochemical stability and excellent battery properties, thereby being usefully used as an all-solid-state polymer electrolyte composition such as a lithium-polymer secondary battery, a dye-sensitized solar cell, etc.COPYRIGHT KIPO 2018
Microwave-assisted, regioselective one-pot synthesis of quinolines and bis-quinolines catalyzed by Bi(III) immobilized on triazine dendrimer stabilized magnetic nanoparticles
Asadi, Beheshteh,Landarani-Isfahani, Amir,Mohammadpoor-Baltork, Iraj,Tangestaninejad, Shahram,Moghadam, Majid,Mirkhani, Valiollah,Rudbari, Hadi Amiri
supporting information, p. 71 - 74 (2016/12/23)
Fe3O4-TDSN-Bi(III) was utilized as an efficient and reusable catalyst for the regioselective one-pot synthesis of quinoline derivatives from arylamines, arylaldehydes and methyl propiolate under microwave irradiation and solvent-free conditions. Also, bis-quinolines were obtained in high yields from dialdehydes or diamines. Atom-economy, high to excellent yields, easy work-up, as well as simple catalyst recovery and reusability are the key features of this procedure.
Synthesis and characterization of Bi(III) immobilized on triazine dendrimer-stabilized magnetic nanoparticles: A reusable catalyst for the synthesis of aminonaphthoquinones and bis-aminonaphthoquinones
Asadi, Beheshteh,Mohammadpoor-Baltork, Iraj,Tangestaninejad, Shahram,Moghadam, Majid,Mirkhani, Valiollah,Landarani-Isfahani, Amir
supporting information, p. 6171 - 6184 (2016/07/16)
A new Bi(iii) immobilized triazine dendrimer-stabilized magnetic nanoparticle (Fe3O4@TDSN-Bi(iii)) catalyst was prepared and characterized by FT-IR, TGA, elemental analysis, FE-SEM, TEM, VSM, XRD, XPS and lCP-OES techniques. This catalyst was used efficiently for the preparation of different aminonaphthoquinones via a one-pot three-component reaction of lawsone, aldehydes and amines in EtOH as a green solvent at room temperature. This catalytic system also showed excellent activity in the synthesis of symmetric and unsymmetric bis-aminonaphthoquinones from dialdehyde and/or diamine in high yields and purity via an easy work-up procedure. The easy recovery and reusability of the catalyst make this method attractive for green chemistry.
In vitro cytotoxic activities of 2-alkyl-4,6-diheteroalkyl-1,3,5-triazines: New molecules in anticancer research
Menicagli, Rita,Samaritani, Simona,Signore, Giovanni,Vaglini, Francesca,Dalla Via, Lisa
, p. 4649 - 4652 (2007/10/03)
The cytotoxic activities of new 2-alkyl-4,6-dihetero-(N,O)alkyl-1,3,5- triazines toward selected tumor cell lines have been evaluated, and for the first time, the potential of 2-alkyl-4,6-dialkoxy-1,3,5-triazines has been shown.
