440640-37-9

Upstream product

• 52162-78-4 (E)-3-(2-nitrophenyl)acryloyl chloride 
• 109-89-7 diethylamine 
• 612-41-9 2-nitrocinnamic acid 
• 2315-36-8 2-Chloro-N,N-diethylacetamide 
• 552-89-6 2-nitro-benzaldehyde 
• 6080-83-7 <(N,N-Diethylcarbamoyl)methylidene>triphenylphosphorane 

Downstream Products

• 440640-39-1 trans-N,N-diethyl-o-aminocinnamamide 

Relevant academic research and scientific papers

Indium-mediated microwave-assisted one-pot synthesis of α,β-unsaturated amides

A stereoselective synthesis of α,β-unsaturated-N,N-diethyl amides was achieved by a one-pot reaction of triphenylphosphine, an aromatic aldehyde, and N,N-diethyl chloroacetamide in the presence of indium under microwave-assisted and solvent-free condition.

Microwave-assisted one-pot synthesis of α, β-unsaturated amides under solvent-free conditions

Under microwave-assisted solvent-free conditions a one-pot reaction of triphenylphosphine, an aldehyde and N, N-diethyl chloroacetamide in the presence of zinc dust affords α, β-unsaturated amides stereoselectively in good yield. In comparison with the co

Synthesis of α β,-unsaturated amide via phosphonium ylide

A series of ,-unsaturated amides were prepared by the Wittig reaction of N,N-diethylamidemethylenetriphenylphosphorane ylide with aldehydes with moderate to good yields. Copyright Taylor & Francis Group, LLC.

Photocyclization reactions. Part 8 [1]. Synthesis of 2-quinolone, quinoline and coumarin derivatives using trans-cis isomerization by photoreaction

2-Quinolone 2, quinoline 3, coumarin (2H-1-benzopyran-2-one) 5, and 2H-1-benzopyran hemiacetal 6 were synthesized by photocyclization reaction of trans-o-aminocinnamoyl derivatives trans-1 and trans-o-hydroxycinnamoyl derivatives trans-4. The reaction proceeds through trans-cis isomerization followed by intramolecular cyclization.