441353-29-3

Upstream product

• 495401-21-3 tert-butyl (2S)-2-benzyloxycarbonylamino-6-bromo-5-hydroxyhexanoate 
• 204074-52-2 tert-butyl 2-benzyloxycarbonylamino-4-(2-oxiranyl)butanoate 
• 112157-39-8 Nα-(Benzyloxycarbonyl)-L-lysine tert-butyl ester 
• 127623-77-2 tert-butyl (S)-2-benzyloxycarbonylamino-6-hydroxyhex-5-enoate 
• 107-18-6 allyl alcohol 
• 495401-23-5 (2S,5R)-2-benzyloxycarbonylamino-5-bromomethyl-δ-valerolactone 

Downstream Products

• 441353-28-2 allyl (2S,5R)-2-benzyloxycarbonylamino-5-hydroxy-6-iodohexanoate 
• 495401-25-7 4-[(S)-2-benzyloxycarbonylamino-2-(tert-butyloxycarbonyl)ethyl]-5-[(S)-3-benzyloxycarbonylamino-3-(tert-butyloxycarbonyl)propyl]-1-[(2R,5S)-5-benzyloxycarbonylamino-5-(allyloxycarbonyl)-2-hydroxypentyl]-3-pyridiniumolate 
• 495401-26-8 4-[(S)-2-benzyloxycarbonylamino-2-(tert-butyloxycarbonyl)ethyl]-5-[(S)-3-benzyloxycarbonylamino-3-(tert-butyloxycarbonyl)propyl]-1-[(2R,5S)-5-benzyloxycarbonylamino-5-carboxy-2-hydroxypentyl]-3-pyridiniumolate 

Relevant academic research and scientific papers

A simple and convenient transformation of L-lysine into pyridinoline and deoxypyridinoline, two collagen cross-links of biochemical interest

Starting from L-lysine as the only chiral building block, pyridinoline and deoxypyridinoline are efficiently synthesised, thus mimicking the postranscriptional formation of these collagen cross-links.