441790-64-3

Upstream product

• 441790-48-3 N-(2-hydroxy-3-methoxypropyl)-N-[(phenylmethoxy)carbonyl]glycine ethyl ester 
• 151097-12-0 4-aminomethyl-1-benzylpiperidine-4-ylamine 
• 441790-49-4 N-(3-methoxy-2-oxopropyl)-N-[(phenylmethoxy)carbonyl]glycine ethyl ester 

Downstream Products

• 441790-66-5 tetrahydro-8a-(methoxymethyl)-5-oxo-1'-(4-pyridinyl)spiro[imidazo[1,2-a]pyrazine-2(3H),4'-piperidine]-7(1H)-carboxylic acid phenylmethyl ester 
• 441790-68-7 tetrahydro-8a-(methoxymethyl)-1-methyl-5-oxo-1'-(4-pyridinyl)spiro[imidazo[1,2-a]pyrazine-2(3H),4'-piperidine]-7(1H)-carboxylic acid phenylmethyl ester 
• 441790-65-4 C₂₀H₂₈N₄O₄ 

Relevant academic research and scientific papers

Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors1-4 V. A series of new derivatives containing a spiro[imidazo[1,2-a]pyrazine-2(3H),4′-piperidin]-5(1H)-one scaffold

We have already reported unique compounds containing a N,O-spiro acetal structure as an orally active factor Xa (FXa) inhibitor. This time, we described a N,N-spiro acetal structure as an analogue of the N,O-spiro acetal structure for an orally active FXa