4419-57-2

Basic information

• Product Name: 1-Pyrrolizino-1-pentanone
• Synonyms: 1-(1-Oxopentyl)pyrrolidine;1-Pyrrolizino-1-pentanone;1-Valerylpyrrolidine
• CAS NO: 4419-57-2
• Molecular Formula: C₉H₁₇NO
• Molecular Weight: 155.2374
• Mol File: 4419-57-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 263.4°Cat760mmHg
• Flash Point: 110.6°C
• Appearance: /
• Density: 0.966g/cm³
• Vapor Pressure: 0.0103mmHg at 25°C
• Refractive Index: 1.473
• CAS DataBase Reference: 1-Pyrrolizino-1-pentanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolizino-1-pentanone(4419-57-2)
• EPA Substance Registry System: 1-Pyrrolizino-1-pentanone(4419-57-2)

Safety Data

• Hazardous Substances Data: 4419-57-2(Hazardous Substances Data)

Usage

Structure

A ketone derivative containing a pyrrolizine ring and a pentanone chain

Usage

Building block in organic synthesis, used as a precursor in the production of pharmaceuticals and other organic compounds

Physical properties

Colorless liquid, soluble in water, has a distinct odor

Importance

An intermediate in the chemical industry used in the synthesis of drugs and other organic compounds

InChI:InChI=1/C9H17NO/c1-2-3-6-9(11)10-7-4-5-8-10/h2-8H2,1H3

Upstream product

• 123-75-1 pyrrolidine 
• 2173-56-0 n-pentyl n-pentanoate 
• 71-41-0 pentan-1-ol 
• 13991-18-9 1-(pyrrolidin-1-yl)pent-4-yn-1-one 
• 73200-35-8 5-hydroxy-1-(pyrrolidin-1-yl)pentan-1-one 
• 108-29-2 5-methyl-dihydro-furan-2-one 
• 116461-11-1 4-hydroxy-1-(pyrrolidin-1-yl)pentan-1-one 
• 1262219-75-9 1-methyl-4-oxo-4-pyrrolidin-1-ylbutyl diphenylphosphinate 
• 109-99-9 tetrahydrofuran 
• 110-59-8 pentanonitrile 
• 1036648-33-5 5-oxo-5-(pyrrolidin-1-yl)pentan-2-yl 4-methylbenzoate 

Downstream Products

• 6797-49-5 2-butylbenzo[d]oxazole 

Relevant articles and documents

MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS

The present invention relates to novel manganese complexes and their use, inter alia, for homogeneous catalysis in (1) the preparation of imine by dehydrogenative coupling of an alcohol and amine; (2) C-C coupling in Michael addition reaction using nitriles as Michael donors; (3) dehydrogenative coupling of alcohols to give esters and hydrogen gas (4) hydrogenation of esters to form alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di- lactones), or polyesters); (5) hydrogenation of amides (including cyclic dipeptides, lactams, diamide, polypeptides and polyamides) to alcohols and amines (or diamine); (6) hydrogenation of organic carbonates (including polycarbonates) to alcohols or hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (7) dehydrogenation of secondary alcohols to ketones; (8) amidation of esters (i.e., synthesis of amides from esters and amines); (9) acylation of alcohols using esters; (10) coupling of alcohols with water and a base to form carboxylic acids; and (11) preparation of amino acids or their salts by coupling of amino alcohols with water and a base. (12) preparation of amides (including formamides, cyclic dipeptides, diamide, lactams, polypeptides and polyamides) by dehydrogenative coupling of alcohols and amines; (13) preparation of imides from diols.

Electrochemical deoxygenation of primary alcohols

Direct electrolysis of primary alcohols, in the presence of methyl toluate, leads smoothly to the formation of the corresponding deoxygenated product in high yield. Georg Thieme Verlag Stuttgart · New York.

Direct synthesis of N-acylpyrrolidines from tetrahydrofuran and nitriles of aliphatic and aromatic acids on zeolite catalysts under supercritical conditions

The tetrahydrofuran-nitrile (CH3CN, n-C4H 9CN, C6H5CN)-zeolite (faujasites, mordenite, beta, pentasils) system and its transformations under supercritical conditions were studied. The feasibility of d