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442199-19-1

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  • 4-(6-Chloro-pyrimidin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester

    Cas No: 442199-19-1

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442199-19-1 Usage

General Description

The chemical "4-(6-Chloro-pyriMidin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester" is a compound with a molecular formula of C14H20ClN3O3 and a molecular weight of 313.78. It is a derivative of piperidine and is commonly used in the synthesis of pharmaceutical compounds and agrochemicals. 4-(6-Chloro-pyriMidin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester, 98+% C14H20ClN3O3, MW: 313.78 is typically used as an intermediate in the production of various drugs and pesticides. It is a white to off-white solid with a purity of 98% or higher, making it suitable for use in research and development applications.

Check Digit Verification of cas no

The CAS Registry Mumber 442199-19-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,2,1,9 and 9 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 442199-19:
(8*4)+(7*4)+(6*2)+(5*1)+(4*9)+(3*9)+(2*1)+(1*9)=151
151 % 10 = 1
So 442199-19-1 is a valid CAS Registry Number.

442199-19-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 4-(6-chloropyrimidin-4-yl)oxypiperidine-1-carboxylate

1.2 Other means of identification

Product number -
Other names tert-butyl 4-(6-chloropyrimidin-4-yloxy)piperidine-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:442199-19-1 SDS

442199-19-1Relevant articles and documents

Discovery of a potent G-protein-coupled receptor 119 agonist for the treatment of type 2 diabetes

Pola, Suresh,Shah, Shailesh R.,Pingali, Harikishore,Zaware, Pandurang,Thube, Baban,Makadia, Pankaj,Patel, Hoshang,Bandyopadhyay, Debdutta,Rath, Akshyaya,Giri, Suresh,Patel, Jitendra H.,Ranvir,Sundar,Patel, Harilal,Kumar, Jeevan,Jain, Mukul R.

, (2021/03/30)

The ever-growing prevalence of Type-2 diabetes in the world has an urgent need for multiple orally effective agents that can regulate glucose homeostasis. G-Protein coupled receptor 119 (GPR 119) agonists have demonstrated the glucose-dependent insulin secretion and showed beneficial effects on glycemic control in humans and/or relevant animal models. Herein, we describe our efforts towards identification of a potent and oral GPR 119 agonist 13c (ZY-G19), which showed in vitro potency in the cell-based assay and in vivo efficacy without exerting any significant signs of toxicity in relevant animal models.

INDOLYLPYRIMIDINES AS MODULATORS OF GPR119

-

Page/Page column 30, (2012/03/26)

The present invention relates to compounds of Formula (I) that are useful for treating, preventing and/or managing the diseases, disorders, syndromes or conditions modulated by GPR119 receptor activity. The invention also relates to the process for preparation of the compounds, pharmaceutical compositions thereof. The invention further relates to methods of treating, preventing and/or managing diseases, disorders syndromes or conditions associated with the modulation of GPR119 receptor by using either alone or in combinations of Formula (I).

PYRIMIDYL INDOLINE COMPOUND

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Page/Page column 48, (2010/08/07)

It is intended to provide a pyrimidyl indoline compound which structurally differs from compounds used as active ingredients in conventional oral hypoglycemic agents and has excellent hypoglycemic effect. The present invention provides a compound represented by the general formula (I) or a pharmaceutically acceptable salt thereof:

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