442199-32-8

Upstream product

• 16110-09-1 2,5 dichloropyridine 
• 134464-79-2 tert-butyl 4-mercapto-1-piperidinecarboxylate 

Downstream Products

• 442198-99-4 (2E)-3-(4-Chlorophenyl)-N-[(1S)-2-[(2-{4-[(5-chloro-2-pyridyl)thio]-1-piperidinyl}-2-oxoethyl)amino]-2-oxo-1-(2-pyridylmethyl)ethyl]-2-propenamide 

Relevant academic research and scientific papers

Peptide compounds

The present invention relates to a compound of the formula (I)wherein R1 is benzofuranyl substituted by halogen, or styryl substituted by halogen; R2 is substituted hydroxy, substituted mercapto or substituted sulfonyl; and X is or pharmaceutically acceptable salts thereof. The compound (1) of the present invention and pharmaceutically acceptable salts thereof possess a strong inhibitory activity on the production of nitric oxide (NO), and are useful for prevention and/or treatment of NO-mediated diseases in human being and animals.