134464-79-2

Basic information

• Product Name: tert-butyl 4-mercaptopiperidine-1-carboxylate
• Synonyms: tert-butyl 4-mercaptopiperidine-1-carboxylate;1-BOC-4-MERCAPTO-PIPERIDINE;tert-Butyl 4-Mercaptopiperidin-1-carboxylate;tert-butyl 4-sulfanylpiperidine-1-carboxylate;1-tert-Butoxycarbonylpiperidine-4-thiol;1-Boc-piperidine-4-thiol;1-Piperidinecarboxylic acid, 4-mercapto-, 1,1-dimethylethyl ester
• CAS NO: 134464-79-2
• Molecular Formula: C₁₀H₁₉NO₂S
• Molecular Weight: 217.331
• Mol File: 134464-79-2.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 294.23°C at 760 mmHg
• Flash Point: 131.746°C
• Appearance: /
• Density: 1.083g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.509
• PKA: 10.52±0.20(Predicted)
• CAS DataBase Reference: tert-butyl 4-mercaptopiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-mercaptopiperidine-1-carboxylate(134464-79-2)
• EPA Substance Registry System: tert-butyl 4-mercaptopiperidine-1-carboxylate(134464-79-2)

Safety Data

• Hazardous Substances Data: 134464-79-2(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-mercaptopiperidine-1-carboxylate is a chemical compound with the molecular formula C11H21NO2S. It is a derivative of piperidine and contains a tert-butyl and a mercapto group. This chemical is commonly used in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. Its structure and reactivity make it useful in the synthesis of various compounds, including those with biological activity. Tert-butyl 4-mercaptopiperidine-1-carboxylate is also used as a building block in the development of new materials and is a valuable reagent in chemical research and development.

InChI:InChI=1/C10H19NO2S/c1-10(2,3)13-9(12)11-6-4-8(14)5-7-11/h8,14H,4-7H2,1-3H3

Upstream product

• 141699-66-3 1-tert-Butyloxycarbonyl-4-(acetylsulfanyl)piperidine 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 141699-59-4 1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 333986-94-0 4-(4-nitrophenylsulfanyl)piperidine-1-carboxylic acid tert-butyl ester 
• 1373131-17-9 tert-butyl 4-sulfanylidenepiperidin-1-carboxylate 

Downstream Products

• 1129458-62-3 tert-butyl 4-(1-(4-methoxybenzyl)-4-(4-amino-2-fluorophenoxy)-1H-pyrazolo[3,4-b]pyridin-3-ylthio)piperidine-1-carboxylate 
• 1453834-85-9 N-(2-(1H-pyrazol-1-yl)benzyl)-8-isopropyl-2-(piperidin-4-ylsulfonyl)pyrazolo[1,5-a][1,3,5]triazin-4-amine 
• 333985-88-9 tert-butyl 4-(pyridin-2-ylthio)piperidine-1-carboxylate 
• 159503-92-1 tert-butyl 4-(benzylsulfanyl)piperidine-1-carboxylate 

Relevant articles and documents

BORON CONTAINING COMPOUNDS AND THEIR USES

The present disclosure contemplates novel boron-containing compounds and their uses as active agents that exhibit pesticidal activity such as antimicrobial, insecticidal, arachnicidal, and/or anti parasitic activity. An agrochemical composition containing such a compound and its use in, animal health, agriculture, or horticulture is also contemplated. A method for promoting plant performance and/or controlling, reducing, preventing, ameliorating, or inhibiting microbes, insects, arachnids, and/or parasites on or in an animal, a plant, a plant part, plant propagation material, and/or harvested fruits or vegetables is also contemplated.

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

no abstract published

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

This invention relates to compounds having structural Formula I: and pharmaceutically acceptable salts thereof which are inhibitors of the Renal Outer Medullary Potassium (ROMK) channel (Kirl.1). The compounds of Formula I are useful as diuretics and natriuretics and therefore are useful for the therapy and prophylaxis of disorders resulting from excessive salt and water retention, including cardiovascular diseases such as hypertension and chronic and acute heart failure