4426-63-5

Basic information

• Product Name: Oxiranemethanol, a-methyl-3-phenyl-
• CAS NO: 4426-63-5
• Molecular Formula: C10H12O2
• Molecular Weight: 164.204
• Mol File: 4426-63-5.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Oxiranemethanol, a-methyl-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranemethanol, a-methyl-3-phenyl-(4426-63-5)
• EPA Substance Registry System: Oxiranemethanol, a-methyl-3-phenyl-(4426-63-5)

Safety Data

• Hazardous Substances Data: 4426-63-5(Hazardous Substances Data)

Upstream product

• 36004-04-3 ethyl (E)-1-phenylbut-1-en-3-ol 
• 104974-60-9 rac-(Z)-4-phenylbut-3-en-2-ol 
• 17488-65-2 4-phenylbut-3-en-2-ol 
• 6249-79-2 1-(3-phenyloxiran-2-yl)ethanone 

Downstream Products

• 32426-79-2 1-((prop-1-enyloxy)methyl)benzene 
• 32426-80-5 (Z)-((prop-1-en-1-yloxy)methyl)benzene 
• 52755-38-1 1-phenyl-2-buten-1-ol 
• 121618-63-1 tert-Butyl-dimethyl-[1-((2R,3S)-3-phenyl-oxiranyl)-ethoxy]-silane 
• 55775-43-4 2-Chloro-3,4-epoxy-4-phenylbutane 
• 110379-57-2 (S)-((S)-5-Methyl-[1,3]dioxolan-4-yl)-phenyl-methanol 
• 135787-84-7 2-(1-Bromo-ethyl)-3-phenyl-oxirane 
• 62763-33-1 (+/-)-3-hydroxy-1-phenyl-2-butanone 
• 55091-68-4 3-phenyl-5-methyl-2,5-dihydrofuran-2-one 
• 34501-28-5 (3-methyl-oxiranyl)-phenyl-methanol 

Relevant articles and documents

Switchable asymmetric bio-epoxidation of α,β-unsaturated ketones

Efficient asymmetric bio-epoxidation of electron-deficient α,β-unsaturated ketones was realized via a tandem reduction-epoxidation-dehydrogenation cascade, which proceeds in a switchable manner to afford either chiral epoxy ketones or allylic epoxy alcoho

Enantioselective epoxidation with chiral MnIII(salen) catalysts: Kinetic resolution of aryl-substituted allylic alcohols

A set of aryl-substituted allylic alcohols rac-2 has been epoxidized by chiral Mn(salen*) complexes 1 as the catalyst and iodosyl benzene (PhIO) as the oxygen source. Whereas one enantiomer of the allylic alcohol 2 is preferentially epoxidized to give the threoor cis-epoxy alcohol 3 (up to 80% ee) as the main product (dr up to >95:5), the other enantiomer of 2 is enriched (up to 53% ee). In the case of 1,1-dimethyl-1,2-dihydronaphthalen-2-ol (2c), the CH oxidation to the enone 4c proceeds enantioselectively and competes with the epoxidation. The absolute configurations of the allylic alcohols 2 and their epoxides 3 have been determined by chemical correlation or CD spectroscopy. The observed diastereo- and enantioselectivities in the epoxidation reactions are rationalized in terms of a beneficial interplay between the hydroxy-directing effect and the attack along the Katsuki trajectory.

Carbodiimide-Promoted Olefin Epoxidation with Aqueous Hydrogen Peroxide

Commercially available carbodiimides in hydroxylic solvents containing hydrogen peroxide with mildly basic or acidic catalysts have been found to promote the epoxidation of olefins. A commercially available 30% aqueous solution of hydrogen peroxide serves as the oxidant for this process. The presumed reactive species is a peroxyisourea generated in situ by the addition of hydrogen peroxide to the carbodiimide.