55091-68-4Relevant articles and documents
Microwave assisted Suzuki reactions for the preparation of the antifungal 3-aryl-5-methyl-2,5-dihydrofuran-2-ones
Mathews, Christopher J.,Taylor, John,Tyte, Melloney J.,Worthington, Paul A.
, p. 538 - 540 (2005)
The Suzuki cross-coupling reaction of arylboronic acids with a bromo-furanone has been developed to prepare a series of substituted 2,5-dihydrofuran-2-ones related to the fungal metabolite, incrustoporin. A protocol of microwave heating was introduced to improve synthesis throughput. Georg Thieme Verlag Stuttgart.
Small changes result in large differences: Discovery of (-)-incrustoporin derivatives as novel antiviral and antifungal agents
Lu, Aidang,Wang, Jinjin,Liu, Tengjiao,Han, Jian,Li, Yinhui,Su, Min,Chen, Jianxin,Zhang, Hui,Wang, Lizhong,Wang, Qingmin
, p. 8799 - 8807 (2015/04/22)
On the basis of the structure of natural product (-)-incrustoporin (1), a series of lactone compounds 4a-i and 5a-i were designed and synthesized from nitroolefin. The antiviral and antifungal activities of these compounds were evaluated in vitro and in v
Small changes result in large differences: Discovery of (-)-incrustoporin derivatives as novel antiviral and antifungal agents
Lu, Aidang,Wang, Jinjin,Liu, Tengjiao,Han, Jian,Li, Yinhui,Su, Min,Chen, Jianxin,Zhang, Hui,Wang, Lizhong,Wang, Qingmin
, p. 8799 - 8807 (2014/11/08)
On the basis of the structure of natural product (-)-incrustoporin (1), a series of lactone compounds 4a-i and 5a-i were designed and synthesized from nitroolefin. The antiviral and antifungal activities of these compounds were evaluated in vitro and in v