6249-79-2

Basic information

• Product Name: Ethanone, 1-(3-phenyloxiranyl)-
• CAS NO: 6249-79-2
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Mol File: 6249-79-2.mol
• Article Data: 53

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(3-phenyloxiranyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(3-phenyloxiranyl)-(6249-79-2)
• EPA Substance Registry System: Ethanone, 1-(3-phenyloxiranyl)-(6249-79-2)

Safety Data

• Hazardous Substances Data: 6249-79-2(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(3-phenyloxiranyl)- is a chemical compound that is also known as 1-acetyl-3-phenyl-2,3-epoxypropane. It is a colorless liquid with a sweet, fruity odor. Ethanone, 1-(3-phenyloxiranyl)- is used in the production of various pharmaceuticals, including antiviral and antibacterial agents. It is also used in the synthesis of certain fragrances and as a flavoring agent in foods and beverages. Additionally, it is a key intermediate in the preparation of other organic compounds, such as resins and polymers. Despite its useful applications, ethanone, 1-(3-phenyloxiranyl)- should be handled with caution as it may be harmful if ingested or inhaled in high concentrations.

Upstream product

• 100-52-7 benzaldehyde 
• 78-95-5 chloroacetone 
• 536-74-3 phenylacetylene 
• 104974-60-9 rac-(Z)-4-phenylbut-3-en-2-ol 
• 73922-81-3 4-phenyl-but-3-yn-2-ol 
• 84033-94-3 (3R,4S)-3-Bromo-4-hydroxy-4-phenyl-butan-2-one 
• 598-31-2 1-bromoacetone 
• 937-53-1 (Z)-4-phenylbut-3-en-2-one 
• 1896-62-4 (E)-benzalacetone 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 19190-80-8 methyl 3-Phenylglycidate 
• 16812-43-4 bis(trimethylstannyl)methane 
• 53309-95-8 (+/-)-2-amino-4-phenylbut-3-ene 
• 19202-21-2 1-trans-cinnamoylpyrrolidine 

Downstream Products

• 21875-88-7 3-Phenylmercapto-4-phenyl-4-hydroxy-butanon-⁽²⁾ 
• 93-91-4 1-phenylbutan-1,3-dione 
• 65-85-0 benzoic acid 
• 146388-50-3 (3S,4R)-3,4-epoxy-4-phenylbutan-2-one 
• 146388-52-5 (2S,3R,4R)-(+)-3,4-epoxy-4-phenyl-2-butanol 
• 146388-51-4 (2S,3S,4S)-(-)-3,4-epoxy-4-phenyl-2-butanol 
• 5381-93-1 1-hydroxy-1-phenyl-3-butanone 
• 98204-74-1 2-(Hydroxy-phenyl-methyl)-1-methyl-cyclopropanol 
• 5355-63-5 3-hydroxy-4-phenyl-2-butanone 
• 65469-88-7 1-phenylbutane-1,3-diol 
• 38087-02-4 1-phenylbutane-2,3-dione 
• 4426-63-5 1-(3-Phenyloxiran-2-yl)ethanol 
• 67-56-1 methanol 
• 46904-25-0 2-benzylidene-3-methyl-2H-benzo[1,4]thiazine 

Relevant articles and documents

Stereodivergent Access to Enantioenriched Epoxy Alcohols with Three Stereogenic Centers via Ruthenium-Catalyzed Transfer Hydrogenation

The resolution technique of stereodivergent reaction on racemic mixtures (stereodivergent RRM) was employed for the first time in ruthenium complex catalyzed transfer hydrogenation of racemic epoxy ketones, providing a new and very simple method that allows access to enantioenriched epoxy alcohols with three stereogenic centers in a one-step fashion. The protocol features simple reaction conditions, practical operation, ability to scale up, and broad group tolerance.

Preparation method of alpha, beta-epoxy ketone compound

The invention provides a method for efficiently preparing an alpha, beta-epoxy ketone compound from alpha-hydrogen-containing alpha-halogenated ketone as a raw material and various aldehydes under theaction of DBU or DBN. Namely the method comprises the steps: slowly and dropwise adding a dichloromethane mixed solution of alpha-halogenated ketone and aldehydes into a dichloromethane solution of DBU or DBN under the conditions of inert gas shielding and 20 DEG C below zero, ending a reaction, and then, carrying out separation and purification to obtain the alpha, beta-epoxy ketone compound. The synthesis method provided by the invention is available in raw material, low in cost, simple and easily-controlled in operation, relatively few in side reactions, simple in aftertreatment, relatively high in product yield, capable of greatly reducing the production cost, relatively high in economic benefit and suitable for large-scale industrial production.

Biomimetic Oxidative Deamination Catalysis via ortho-Naphthoquinone-Catalyzed Aerobic Oxidation Strategy

An ortho-naphthoquinone-catalyzed oxidative deamination reaction has been developed where the molecular oxygen and water serve as the sole oxidant and nucleophile. The current aerobic deamination reaction proceeds via the ketimine formation between ortho-naphthoquinones and amines followed by the prototropic rearrangement and hydrolysis by water, representing a biomimetic oxidative deamination of amine species in the human body by the liver and kidneys. The compatibility of ortho-naphthoquinone organocatalysts with molecular oxygen and water opens up a new biomimetic catalyst system that can function as versatile deaminases for a variety of amine-containing molecules such as amino acids and DNA nuclear bases.