442663-40-3Relevant academic research and scientific papers
Total synthesis of ecteinascidin 743
Endo, Atsushi,Yanagisawa, Arata,Abe, Masanao,Tohma, Shigemitsu,Kan, Toshiyuki,Fukuyama, Tohru
, p. 6552 - 6554 (2002)
The total synthesis of ecteinascidin 743 (1), an extremely potent antitumor agent, has been accomplished. The synthesis features Ugi's 4CC reaction, intramolecular Heck reaction, phenol-aldehyde cyclization, and acid-induced intramolecular sulfide formation. Copyright
