4428-98-2

Basic information

• Product Name: N-Cyanomethanimidic acid ethyl ester
• Synonyms: N-Cyanomethanimidic acid ethyl ester;(Ethoxymethylene)cyanamide;Ethyl N-cyanoformimidate;Ethyl N-cyanomethanimidate;(E)-(ethyl N-cyanoMethenecarboxiMidate);(Z)-Ethyl N-cyanoformimidate;ethyl cyanoimidoformate;METHANIMIDIC ACID, N-CYANO-, ETHYL ESTER
• CAS NO: 4428-98-2
• Molecular Formula: C₄H₆N₂O
• Molecular Weight: 98
• Mol File: 4428-98-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 116℃
• Flash Point: 24℃
• Appearance: /
• Density: 0.94
• CAS DataBase Reference: N-Cyanomethanimidic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Cyanomethanimidic acid ethyl ester(4428-98-2)
• EPA Substance Registry System: N-Cyanomethanimidic acid ethyl ester(4428-98-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 4428-98-2(Hazardous Substances Data)

Usage

Uses

Ethyl Cyanoimidoformate is a useful reagent in the preparation of C-nucleosides as potential HCV agents.

Upstream product

• 420-04-2 CYANAMID 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 105364-26-9 C₇H₆N₄ 
• 59425-39-7 p-Methylphenylaminomethylen-cyanamid 
• 59425-42-2 p-Nitrophenylaminomethylen-cyanamid 
• 77032-18-9 C₉H₉N₃ 
• 62156-20-1 4-amino-8-(β-D-2,3-O-isopropylidene-5-O-tritylribofuranosyl)pyrazolo<1,5-a>-1,3,5-triazine 
• 1591742-15-2 C₃₂H₂₇Cl₆N₅O₄ 
• 1174376-33-0 N-[5-fluoro-2-(4-fluorobenzyloxy)pyrimidin-4-yl]-N'-cyanoformamidine 
• 937784-76-4 N-cyano-N'-[3-(difluoromethoxy)-4-[3-(trimethylsilyl)propoxy]phenyl]methanimidamide 
• 937784-70-8 N-cyano-N'-[3-methoxy-4-[3-(trimethylsilyl)propoxy]phenyl]methanimidamide 
• 937784-66-2 N-cyano-N'-[4-[(4-methylpentyl)oxy]-3-(trifluoromethyl)phenyl]methanimidamide 
• 87633-57-6 2-(5-amino-1H-1,2,4-triazol-1-yl)benzimidazole 
• 278183-10-1 methyl 4-amino-1,3-thiazole-5-carboxylatte 
• 169616-29-9 ethyl 4-amino-1-benzyl-1H-imidazole-5-carboxylate 
• 28610-01-7 Triazolo-triazin IVc 

Relevant articles and documents

Synthesis and evaluation of a collection of purine-like C-nucleosides as antikinetoplastid agents

The kinetoplastid parasites Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp. are the causative agents of neglected tropical diseases with a serious burden in several parts of the world. These parasites are incapable of synthesizing purines de nov

5-FLUORO PYRIMIDINE DERIVATIVES

This present disclosure is related to the field of 5-fluoro pyrimidines and their derivatives and to the use of these compounds as fungicides.

SUBSTITUTED BENZIMIDAZOLES AND THEIR USE FOR INDUCING APOPTOSIS

The invention relates to compounds of formula (I), wherein R represents aryl or heteroaryl, X is a bond, a carbonyl group, a derivative of a carbonyl group, an ethylene group or an ethylenecarbonyl group, R1 is optionally substituted amino or hydroxy, and the substituents R2 to R6 have the meanings given in the specification, to methods of synthesis of such compounds, to pharmaceutical compositions containing compounds of formula (I), to intermediates, to the use of a compounds of formula (I) as a medicament and for the preparation of a pharmaceutical composition for the treatment of neoplastic and autoimmune diseases, and to methods of treatment of neoplastic and autoimmune diseases using such compounds of formula (I) or of pharmaceutical compositions containing same.