442899-68-5

Upstream product

• 243468-74-8 methyl (2Z,4E,10E,6R,7S,8S)-7-hydroxy-11-iodo-2-methoxy-4,6,8,10-tetramethyl-2,4,10-undecatrienoate 
• 442899-64-1 C₃₃H₆₃BO₈Si₂ 
• 442899-65-2 (2E,8E)-(4R,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-9-iodo-2,4,6,8-tetramethyl-nona-2,8-dienoic acid methyl ester 
• 442899-95-8 (3S,4R,5S,6S,7R,8R)-6-(tert-Butyl-dimethyl-silanyloxy)-8-(3,4-dimethoxy-benzyloxy)-3-methoxy-5,7-dimethyl-4-triethylsilanyloxy-nonane-1,2-diol 
• 442899-67-4 4-[(1R,2R,3S,4S,5R,6S)-3-(tert-Butyl-dimethyl-silanyloxy)-6-methoxy-1,2,4-trimethyl-5-triethylsilanyloxy-oct-7-ynyloxymethyl]-1,2-dimethoxy-benzene 
• 214198-34-2 [3S,4R,5R,6S,7R,8R]-6-[(tert-butyldimethylsilyl)oxy]-8-[(3,4-dimethoxybenzyl)oxy]-5,7-dimethyl-3-methoxy-4-[(triethylsilyl)oxy]non-1-ene 
• 442899-66-3 (2R,3R,4S,5S,6R,7R)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(3,4-dimethoxy-benzyloxy)-2-methoxy-4,6-dimethyl-3-triethylsilanyloxy-octanal 
• 243468-93-1 methyl (2Z,4E,10E,6R,7S,8S)-7-(tert-butyldimethylsilyl)-11-iodo-2-methoxy-4,6,8,10-tetramethyl-2,4,10-undecatrienoate 
• 243468-76-0 (3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexan-1-ol 
• 243468-89-5 tert-Butyl-{(1S,2S)-1-[(R)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-pent-4-ynyloxy}-dimethyl-silane 
• 243468-78-2 (2E,8E,4R,5S,6S)-5-(tert-butyldimethylsilyloxy)-1-iodo-2,4,6,8-tetramethyl-2,8-nonadien-1-ol 
• 243468-87-3 (3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexanal 
• 243468-86-2 tert-Butyl-{(1S,2S)-1-[(R)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-but-3-enyloxy}-dimethyl-silane 
• 243468-92-0 (2E,4R,5S,6S,8E)-5-((tert-butyldimethylsilyl)oxy)-9-iodo-2,4,6,8-tetramethylnona-2,8-dienal 

Relevant academic research and scientific papers

Total synthesis of (-)-bafilomycin A1

A highly stereoselective total synthesis of (-)-bafilomycin A1, the naturally occurring enantiomer of this potent vacuolar ATPase inhibitor, is described. The synthesis features the highly stereoselective aldol reaction of methyl ketone 8b and