4431-83-8Relevant academic research and scientific papers
Preparation method of bis(dimethoxyethoxy)methane
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Paragraph 0041-0056, (2019/12/08)
Relating to the technical field of chemical synthesis, the invention discloses a preparation method of bis(dimethoxyethoxy)methane. The method includes the steps of: subjecting ethylene glycol monomethyl ether and formaldehyde to aldol condensation reaction under the action of an acid catalyst to prepare bis(dimethoxyethoxy)methane; wherein the molar ratio of formaldehyde to ethylene glycol monomethyl ether is 1:2-4; the dosage of the acid catalyst is 0.1-10%; the reaction temperature is 60-140DEG C, and the reaction time is 0.5-24h. The method provided by the invention utilizes acid to catalyze the reaction of ethylene glycol monomethyl ether and formaldehyde to generate bis(dimethoxyethoxy)methane, and belongs to economical reaction, the product includes water and is free of byproduct, and the catalyst has small corrosion to equipment, therefore the method is a clean bis(dimethoxyethoxy)methane synthesis method capable of recycling the catalyst, and is suitable for industrial continuous production.
New substrates for the preparation of electroactive materials: The syntheses of chiral tetrathiafulvalene derivatives with hydroxy-functionalised butane-1,4-dithio bridges
Horley, Graeme A.,Ozturk, Turan,Turksoy, Figen,Wallis, John D.
, p. 3225 - 3231 (2007/10/03)
The syntheses of two derivatives of TTF containing (2R,3R)-2,3-dihydroxybutane-1,4-dithio bridges is described, for use in the preparation of chiral hydrogen bonded radical cation salts as potentially electroactive materials. The bridges are introduced by reaction of 2-thioxo-1,3-dithiole-4,5-dithiolate with 1,4-disubstituted derivatives of bis-O-protected butane-2,3-diol to give a bicyclic thione. The X-ray crystal structure of the isopropylidene ketal derivative shows that all four sp3 carbon atoms in the eight-membered ring are displaced to the same side of the dithiole plane. Ease of deprotection led to the use of methoxyethoxymethyl (MEM) protecting groups rather than the ketal. Treatment of the bis-MEM-protected bicyclic thione with mercuric acetate and acetic acid led not only to exchange of the exocyclic sulfur for oxygen but also to removal of just one of the MEM groups, which may have wider synthetic applications.
QUATERNARY AMMONIUM SALTS IN ALKYLATION REACTIONS (SYNTHESIS OF FORMALDEHYDE ACETALS).
Nazaretyan,Torosyan,Babayan
, p. 2396 - 2400 (2007/10/02)
The influence of the nature of the catalyst on the reaction yields was studied in the synthesis of formaldehyde bis( beta -methoxyethyl) and dibenzyl acetals. The acetal yields were not greatly influenced by the nature of the catalyst. The synthesis was also effected in presence of polymeric ammonium salts. In comparison with earlier results, the polymeric salts in this case were more effective than their monomeric analogs.
