15132-01-1

Basic information

• Product Name: 1,4-Diphenyl-1H-pyrazole
• Synonyms: 1,4-Diphenyl-1H-pyrazole;1,4-diphenylpyrazole
• CAS NO: 15132-01-1
• Molecular Formula: C₁₅H₁₂N₂
• Molecular Weight: 220.27
• Mol File: 15132-01-1.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,4-Diphenyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Diphenyl-1H-pyrazole(15132-01-1)
• EPA Substance Registry System: 1,4-Diphenyl-1H-pyrazole(15132-01-1)

Safety Data

• Hazardous Substances Data: 15132-01-1(Hazardous Substances Data)

Upstream product

• 26591-66-2 2-phenyl-1,3-propanedial 
• 64-19-7 acetic acid 
• 100-63-0 phenylhydrazine 
• 536-74-3 phenylacetylene 
• 508191-77-3 3-phenylsydnone 
• 23889-85-2 4-iodo-1-phenyl 1H-pyrazole 
• 98-80-6 phenylboronic acid 
• 1126-00-7 1-phenylpyrazole 
• 13146-23-1 copper(I) phenylacetylenide 
• 5670-65-5 (E)-1-nitro-2-phenyl-1-propene 
• 98-83-9 isopropenylbenzene 
• 98-86-2 acetophenone 
• 122-78-1 phenylacetaldehyde 
• 6415-68-5 N-nitroso-N-phenylglycine 

Relevant articles and documents

1,3-Difunctionalization of β-alkyl nitroalkenes via combination of Lewis base catalysis and radical oxidation

Upon treatment with a Lewis base catalyst, β-alkyl-substituted nitroalkenes could be readily converted into allylic nitro compounds. Examples of either C-1 or C-3 functionalization methods have been reported through nitro-elimination, giving alkene products. In this work, successful 1,3-difunctionalization was achieved through a synergetic Lewis base catalysis and TBHP radical oxidation, giving vinylic alkoxyamines in good to excellent yields. This work further extended the general synthetic application of β-alkyl nitroalkenes.

Cu-catalysed pyrazole synthesis in continuous flow

The synthesis of 1,4-disubstituted pyrazoles via the cycloaddition reaction of sydnones and terminal alkynes has been achieved employing silica-supported copper catalysts. Furthermore, this methodology has been successfully implemented in continuous flow

One-pot synthesis of 1,4-disubstituted pyrazoles from arylglycines via copper-catalyzed sydnone-alkyne cycloaddition reaction

A robust method for constructing 1,4-pyrazoles from arylglycines was developed using the copper-catalyzed sydnone-alkyne cycloaddition reaction. The procedure offers a straightforward and general route to the pyrazole heterocycle through a three-step one-pot procedure.