443915-51-3

Basic information

• Product Name: 4-[4-(2-Methoxyethyl)piperazin-1-yl]aniline
• Synonyms: 4-[4-(2-Methoxyethyl)piperazin-1-yl]aniline;4-[4-(2-methoxyethyl)-1-piperazinyl]phenylamine
• CAS NO: 443915-51-3
• Molecular Formula: C13H21N3O
• Molecular Weight: 235.32534
• Mol File: 443915-51-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[4-(2-Methoxyethyl)piperazin-1-yl]aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-(2-Methoxyethyl)piperazin-1-yl]aniline(443915-51-3)
• EPA Substance Registry System: 4-[4-(2-Methoxyethyl)piperazin-1-yl]aniline(443915-51-3)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 443915-51-3(Hazardous Substances Data)

Upstream product

• 6269-89-2 1-(4-Nitrophenyl)piperazine 
• 13484-40-7 1-(2-methoxyethyl)piperazine 
• 350-46-9 4-Fluoronitrobenzene 

Relevant articles and documents

PYRIMIDOPYRIMIDINONES USEFUL AS WEE-1 KINASE INHIBITORS

The present invention relates to compounds that are useful as inhibitors of the activity of Wee-1 kinase. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in the treatment of cancer and methods of treating cancer.

IMIDAZOPYRAZINE SYK INHIBITORS

Certain imidazopyrazines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suf-fering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of an imidazopyrazine compound effective to reduce signs or symptoms of the disease or dis-order are provided.

2-AMINOPYRIMIDINE AND 2-AMINOPYRIDINE-4-CARBAMATES FOR USE IN THE TREATMENT OF AUTOIMMUNE DISEASES

The present invention relates to pyrimidine or pyridine carbamate compounds having the general Formula (1) and pharmaceutically acceptable salts or derivatives thereof. Also included are methods of treatment of various diseases and conditions, including inflammation, inhibition of T cell activation and proliferation, arthritis, organ transplant, ischemic or reperfusion injury, myocardial infarction, stroke, multiple sclerosis, inflammatory bowel disease, Crohn's disease, lupus, hypersensitivity, type 1 diabetes, psoriasis, dermatitis, Hashimoto's thyroiditis, Sjogren's syndrome, autoimmune hyperthyroidism, Addison's disease, autoimmune diseases, glomerulonephritis, allergic diseases, asthma, hayfever, eczema, cancer, colon carcinoma, thymoma, just to name a few, in a mammal, the methods comprising administering a therapeutically-effective amount a compound of Formula I, or a salt or derivative form thereof, as described above.