444150-18-9

Upstream product

• 198268-99-4 4-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranos-1-yl)-but-2-enoic ethyl ester 
• 120520-77-6 2-{(2R,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-[(benzyloxy)methyl] tetrahydro-2H-pyran-2-yl}acetaldehyde 
• 82659-52-7 1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-2-propene 
• 87256-50-6 4-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranos-1-yl)-but-2-en-1-ol 
• 80300-30-7 1-O-acetyl-2,3,4,6-tetra-O-benzyl-D-glucopyranose 
• 102959-64-8 triphenyl-(α-carbethoxy-β-carboxyethyl)phosphonium betaine 

Downstream Products

• 444150-28-1 2-acetamido-2-[3-benzyloxy-4-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranos-1-ylmethyl)benzyl]malonic diethyl ester 
• 444150-22-5 4-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranos-1-ylmethyl)-3-benzyloxybenzoic ethyl ester 
• 444150-24-7 1-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranos-1-ylmethyl)-2-benzyloxy-4-hydroxymethylbenzene 
• 444150-26-9 1-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranos-1-ylmethyl)-2-benzyloxy-4-bromomethylbenzene 
• 444150-20-3 4-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranos-1-ylmethyl)-3-hydroxybenzoic ethyl ester 

Relevant academic research and scientific papers

A novel general route for the synthesis of C-glycosyl tyrosine analogues.

A general method for the synthesis of C-glycosyl amino acids is described here. The stereoisomerically pure tyrosine analogues alpha-L-4 and beta-L-6 are prepared in reasonable overall yields from allyl derivatives 10 and 11. The key step is a benzannulation procedure which is employed in the creation of the aromatic ring that bears the amino acid function.