444166-93-2

Upstream product

• 19718-49-1 4-amino-3-iodobenzoic acid methyl ester 
• 814-68-6 acryloyl chloride 

Downstream Products

• 1030373-98-8 C₁₄H₁₅NO₃ 
• 444167-04-8 3-[(2-iodo-4-methoxycarbonyl-phenyl)-methyl-carbamoyl]-pyrrole-1-carboxylic acid tert-butyl ester 
• 444166-98-7 3-iodo-4-[methyl-(1H-pyrrole-3-carbonyl)-amino]-benzoic acid methyl ester 
• 444166-95-4 4-(acryloyl-methyl-amino)-3-iodo-benzoic acid methyl ester 

Relevant academic research and scientific papers

Design and synthesis of 1-benzazepine derivatives by strategic utilization of Suzuki-Miyaura cross-coupling, aza-Claisen rearrangement and ring-closing metathesis

A new and simple methodology has been realized for the synthesis of 7-substituted 2,3,4,5-tetrahydro-1-benzazepine derivatives with Suzuki-Miyaura cross-coupling, aza-Claisen rearrangement and ring-closing metathesis (RCM) the key steps. Here, o-allylacet

Aryl radical cyclisation onto pyrroles

The intramolecular cyclisation of aryl radicals onto a pyrrole is studied. The cyclisation allows the synthesis of either the spiropyrrolidinyloxindole or the pyrrolo[3,2-c]quinoline skeleton depending on the nature of the protecting group at the N-pyrrole atom. The regiochemistry of the cyclisation is not affected by the substituents on the benzene ring. Some limitations on the utility of tosylmethylisocyanide in pyrrole synthesis are also reported.