444310-19-4Relevant academic research and scientific papers
Entry to β-alkoxyacrylates via gold-catalyzed intermolecular coupling of alkynoates and allylic ethers
Park, Sae Rom,Kim, Cheoljae,Kim, Dong-Gil,Thrimurtulu, Neetipalli,Yeom, Hyun-Suk,Jun, Jungho,Shin, Seunghoon,Rhee, Young Ho
, p. 1166 - 1169 (2013/05/09)
The first gold-catalyzed intermolecular coupling of alkynoates and allylic ethers invoking alkoxy addition and [3,3]-sigmatropic rearrangement as the key mechanism has been developed. Remarkably, the reaction showed complete chemoselectivity toward the pathway initiated by the alkoxy addition to alkynes. This unprecedented reactivity led to a new access to diversely substituted β-alkoxyacrylates in a highly efficient manner.
