444613-83-6

Upstream product

• 72505-21-6 4-trifluoromethylbenzthioamide 
• 444615-63-8 diethyl 2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4,5-dicarboxylate 
• 444615-64-9 {2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4,5-diyl}dimethanol 
• 444613-21-2 ethyl 2-[4-(chlorosulfonyl)phenoxy]-2-methylpropanoate 
• 444613-23-4 ethyl 2-methyl-2-(4-sulfanylphenoxy)propanoate 
• 444613-51-8 ethyl 2-{4-[({4-(hydroxymethyl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}-2-methylpropanoate 
• 7143-01-3 Methanesulfonic anhydride 

Downstream Products

• 444613-82-5 2-(4-{[(4-{[4-(4-methoxyphenyl)piperazin-1-yl]methyl}-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl)methyl]sulfanyl}phenoxy)-2-methylpropanoic acid ethyl ester 

Relevant academic research and scientific papers

An efficient synthesis of a potent PPARpan agonist

An efficient synthesis of 2-{4-[({4-{[4-(4-methoxyphenyl)-piperazin-1-yl] methyl}-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)thio]phenoxy} -2-methylpropanoic acid (1), a potent PPARpan agonist, is described. The seven-step synthesis, which affo