444643-08-7

Upstream product

• 455-36-7 1-(3-fluorophenyl)ethanone 
• 2627-86-3 (S)-1-phenyl-ethylamine 

Downstream Products

• 444643-20-3 C₈H₆O₄*C₁₆H₁₈FN 
• 761390-58-3 (R)-(-)-1-(3-fluorophenyl)ethylamine 
• 444643-09-8 (S)-3-fluoro-α-methylbenzylamine 

Relevant academic research and scientific papers

Practical synthesis of optically active fluorine-substituted α-phenylethylamines by retardation of hydrogenolytic cleavage at benzylic position

High regioselectivity in hydrogenolysis of bis(α-methylbenzyl)amines having a fluorine atom on aromatic ring results from retardation of hydrogenolytic cleavage at benzylic position of fluorine-substituted aromatic ring.

Process for producing optically active 1-(fluoro- or trifluoromethyl-substituted phenyl) ethylamine and process for purifying same

An optically active 1-(fluoro- or trifluoromethyl-substituted phenyl)ethylamine is produced with high optical purity and in an industrially simple and efficient manner by asymmetrically reducing an optically active imine, obtained by dehydration and conde