444753-80-4

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 56613-80-0 D-2-phenylglycinol 
• 444753-78-0 N-methyl-N-[3-benzyloxy-2-(2`-oxo-ethyl)]phenyl-(S)-valine benzyl ester 
• 444753-77-9 N-methyl-N-[3-benzoxy-2-(2`-hydroxyethyl)]phenyl-(S)-valine benzyl ester 
• 100-39-0 benzyl bromide 

Downstream Products

• 444753-81-5 (S)-2-({3-Benzyloxy-2-[(S)-2-((R)-2-hydroxy-1-phenyl-ethylamino)-2-methoxycarbonyl-ethyl]-phenyl}-methyl-amino)-3-methyl-butyric acid benzyl ester 
• 444753-83-7 N-methyl-N-[3-benzoxy-2-[(S)-2`-(tert-butyloxycarbonyl)amino-2`-methoxycarbonyl]ethyl]phenyl-(S)-valine benzyl ester 
• 444753-79-1 (S)-2-({3-Benzyloxy-2-[(S)-2-cyano-2-((R)-2-hydroxy-1-phenyl-ethylamino)-ethyl]-phenyl}-methyl-amino)-3-methyl-butyric acid benzyl ester 

Relevant academic research and scientific papers

Synthesis of 7-substituted benzolactam-V8s and their selectivity for protein kinase C isozymes.

[reaction: see text] Condensation of L-valine benzyl ester toluenesulfonic acid salt with a substituted cyclohexadione followed by aromatization with the assistance of NBS provides an N-aryl L-valine benzyl ester. This intermediate is converted into 7-sub