445-66-9

Usage

Uses

Used in Pharmaceutical Industry:
4-AMINO-3,5-DINITROBENZOTRIFLUORIDE is used as a synthetic precursor for the production of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows for the creation of diverse medicinal compounds with potential applications in treating a wide range of diseases and conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 4-AMINO-3,5-DINITROBENZOTRIFLUORIDE is utilized as a key intermediate in the synthesis of pesticides and other crop protection agents. Its incorporation into these products helps enhance crop yields and protect plants from pests and diseases, thereby ensuring food security and agricultural productivity.
Used as a Reagent in Chemical Analysis:
4-AMINO-3,5-DINITROBENZOTRIFLUORIDE is employed as a reagent in the qualitative and quantitative analysis of aliphatic amines and amino acids. Its ability to react with these compounds allows for accurate determination of their concentrations in various samples, which is vital in research, quality control, and environmental monitoring.

InChI:InChI=1/C7H4F3N3O4/c8-7(9,10)3-1-4(12(14)15)6(11)5(2-3)13(16)17/h1-2H,11H2

Upstream product

• 393-75-9 4-chloro-3,5-dinitrobenzotrifluoride 
• 17811-45-9 phenyl 2,6-dinitro-4-trifluoromethylphenyl ether 
• 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzeneamine 
• 401-99-0 3,5-dinitrobenzotrifluoride 
• 109-73-9 N-butylamine 

Downstream Products

• 38727-36-5 4-(2,6-Dinitro-4-trifluoromethyl-phenylamino)-2,3,5,6-tetrafluoro-benzonitrile 
• 2078-01-5 3-nitro-5-trifluoromethyl-1,2-phenylenediamine 
• 130535-62-5 N,N-Dimethyl-N'-(2,6-dinitro-4-trifluoromethylphenyl)formamidine 

Relevant academic research and scientific papers

Electrochemical synthesis of nitroanilines

Alkylamines and amides are readily prepared by nucleophilic aromatic substitution of hydrogen in nitroarenes by electrochemical oxidation. Useful yields (15-85%) are achieved in a simple direct and regioselective amination process. The synthetic method has been examined in the absence and presence of external bases, used to promote the first step of the nucleophilic aromatic substitution reaction, i.e. the nucleophilic attack. In both cases, good results were obtained. The unreacted starting material can easily be recovered at the end of the electrochemical oxidation process. This new method represents an environmentally favourable route to amino- and amido-substituted nitroaromatic compounds.

19F NMR as an Analytical Tool for Fluorinated Agrochemical Research

19F NMR was utilized to monitor the photodegradation of trifluralin directly in NMR tubes without extraction, cleanup, concentration, or chromatographic separation.Dissipation curves were generated for the parent pesticide and degradation products, and the major products identified by addition of authentic standarts were α-α-α-trifluoro-2,6-dinitro-N-propyl-p-toluidine (II), α,α,α-trifluoro-2,6-dinitro-p-toluidine (III), and 2-ethyl-7-nitro-5-(trifluoromethyl)benzimidazole (VII).Numerous peaks were observed in the spectra that may represent labile intermediates not generally observed with other analytical techniques.Keywords: 19F NMR; trifluralin; photodegradation

Benzimidazole insecticides

2,6-Di(fluoroalkyl)-4-nitrobenzimidazoles and certain N-acyl derivatives thereof, including sulfonates, thiocarboxamides, and carboxylates, are used to control a broad spectrum of mites and insects with particularly good effect against members of the orde

Quinoxaline derivatives as immune regulants

Novel quinoxaline derivatives, useful as immune regulatory agents capable of altering the immune response in mammals.

Control of animal parasites with benzimidazoles

A class of substituted benzimidazoles are useful parasiticides for the systemic control of insects and acarina which feed on living tissues of animals. The compounds, which control both bloodsucking parasites and flesh-eating parasites, are characterized