445-66-9

Basic information

• Product Name: 4-AMINO-3,5-DINITROBENZOTRIFLUORIDE
• Synonyms: 4-AMINO-3,5-DINITROBENZOTRIFLUORIDE;2,6-DINITRO-4-(TRIFLUOROMETHYL)ANILINE;2,6-DINITRO-4-TRIFLUOROMETHYLBENZENAMINE;2,6-DINITRO-4-TRIFLUOROMETHYLBENZENEAMINE;4-AMINO-3,5-DINOTROBENZOTRIFLUORIDE;2,6-dinitro-4-(trifluoromethyl)phenylamine
• CAS NO: 445-66-9
• Molecular Formula: C₇H₄F₃N₃O₄
• Molecular Weight: 251.12
• Product Categories: Amines;C7;Nitrogen Compounds
• Mol File: 445-66-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 144-149 °C(lit.)
• Boiling Point: 313.1 °C at 760 mmHg
• Flash Point: 143.1 °C
• Appearance: /
• Density: 1.686 g/cm³
• CAS DataBase Reference: 4-AMINO-3,5-DINITROBENZOTRIFLUORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-3,5-DINITROBENZOTRIFLUORIDE(445-66-9)
• EPA Substance Registry System: 4-AMINO-3,5-DINITROBENZOTRIFLUORIDE(445-66-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 445-66-9(Hazardous Substances Data)

Usage

General Description

4-AMINO-3,5-DINITROBENZOTRIFLUORIDE is a chemical compound with the molecular formula C7H4N3O4F3. It is a yellow crystalline powder that is primarily used as a precursor in the synthesis of various organic compounds, particularly pharmaceuticals and agrochemicals. It is also used as a reagent in the analysis of aliphatic amines and amino acids. However, it is highly reactive and toxic, and proper safety precautions must be taken when handling and storing this compound. Its chemical properties make it an important building block in the production of a wide range of chemicals and materials.

InChI:InChI=1/C7H4F3N3O4/c8-7(9,10)3-1-4(12(14)15)6(11)5(2-3)13(16)17/h1-2H,11H2

Upstream product

• 393-75-9 4-chloro-3,5-dinitrobenzotrifluoride 
• 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzeneamine 
• 401-99-0 3,5-dinitrobenzotrifluoride 
• 109-73-9 N-butylamine 
• 17811-45-9 phenyl 2,6-dinitro-4-trifluoromethylphenyl ether 

Downstream Products

• 38727-36-5 4-(2,6-Dinitro-4-trifluoromethyl-phenylamino)-2,3,5,6-tetrafluoro-benzonitrile 
• 2078-01-5 3-nitro-5-trifluoromethyl-1,2-phenylenediamine 
• 130535-62-5 N,N-Dimethyl-N'-(2,6-dinitro-4-trifluoromethylphenyl)formamidine 

Relevant articles and documents

Electrochemical synthesis of nitroanilines

Alkylamines and amides are readily prepared by nucleophilic aromatic substitution of hydrogen in nitroarenes by electrochemical oxidation. Useful yields (15-85%) are achieved in a simple direct and regioselective amination process. The synthetic method has been examined in the absence and presence of external bases, used to promote the first step of the nucleophilic aromatic substitution reaction, i.e. the nucleophilic attack. In both cases, good results were obtained. The unreacted starting material can easily be recovered at the end of the electrochemical oxidation process. This new method represents an environmentally favourable route to amino- and amido-substituted nitroaromatic compounds.

Benzimidazole insecticides

2,6-Di(fluoroalkyl)-4-nitrobenzimidazoles and certain N-acyl derivatives thereof, including sulfonates, thiocarboxamides, and carboxylates, are used to control a broad spectrum of mites and insects with particularly good effect against members of the orde

Control of animal parasites with benzimidazoles

A class of substituted benzimidazoles are useful parasiticides for the systemic control of insects and acarina which feed on living tissues of animals. The compounds, which control both bloodsucking parasites and flesh-eating parasites, are characterized