446-46-8

Basic information

• Product Name: Benzenediazonium, 2-fluoro-, tetrafluoroborate(1-)
• CAS NO: 446-46-8
• Molecular Formula: C6H4FN2.BF4
• Molecular Weight: 209.914
• Mol File: 446-46-8.mol

Chemical Properties

• CAS DataBase Reference: Benzenediazonium, 2-fluoro-, tetrafluoroborate(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenediazonium, 2-fluoro-, tetrafluoroborate(1-)(446-46-8)
• EPA Substance Registry System: Benzenediazonium, 2-fluoro-, tetrafluoroborate(1-)(446-46-8)

Safety Data

• Hazardous Substances Data: 446-46-8(Hazardous Substances Data)

Upstream product

• 348-54-9 2-Fluoroaniline 
• 7632-00-0 sodium nitrite 

Downstream Products

• 89346-48-5 2-(2-fluorophenyl)pyridine 
• 89346-50-9 4-(2-fluorophenyl)pyridine 
• 89346-49-6 3-(2-fluorophenyl)pyridine 
• 321-60-8 2-fluorobiphenyl 
• 63686-21-5 [Ir(CO)Cl(NH:NC₆H₃F-o)(PPh₃)2]BF₄ 
• 63312-07-2 [IrCl₂(o-N₂C₆H₄F)(CO)(PPh₃)2] 
• 1407968-43-7 C₁₂H₁₅FO₂ 
• 1993-03-9 o-fluorophenylboronic acid 
• 342-24-5 o-fluorobenzophenone 
• 388-82-9 2,2'-difluorobiphenyl 
• 29778-27-6 (2-(2-fluorophenyl)ethynyl)benzene 
• 1612831-67-0 (E)-methyl 3-(2-fluorophenyl)-2-(hydroxyimino)propanoate 
• 191930-42-4 methyl 2-amino-3-(2-fluorophenyl)propanoate 
• 876062-39-4 2-(2-fluorophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 

Relevant articles and documents

RhIII-Catalyzed Synthesis of Highly Substituted 2-Pyridones using Fluorinated Diazomalonate

A RhIII-catalyzed strategy was developed for the rapid construction of highly substituted 2-pyridone scaffolds using α,β-unsaturated oximes and fluorinated diazomalonate. The reaction proceeds through direct, site-selective alkylation based on migratory insertion and subsequent cyclocondensation. A wide substrate scope with different functional groups was explored. The requirement of fluorinated diazomalonate was explored for this transformation. The developed methodology was further extended with the synthesis of the bioactive compound.

Phenalenyl Based Aluminum Compound for Catalytic C-H Arylation of Arene and Heteroarenes at Room Temperature

Main group metal based catalysis has been considered to be a cost-effective alternative way to the transition metal based catalysis, due to the high abundance of main group metals in the Earth's crust. Among the main group metals, aluminum is the most abundant (7-8%) in the Earth's crust, making the development of aluminum based catalysts very attractive. So far, aluminum based compounds have been popularly used as Lewis acids in a variety of organic reactions, but chemical transformation demanding a redox based process has never utilized an Al(III) complex as a catalyst. Herein, we tuned the redox noninnocence behavior of a phenalenyl ligand by coupling with Al(III) ion, which subsequently can store the electron upon reduction with K to carry out direct C-H arylation of heteroarenes/mesitylene at ambient temperature. A mechanistic investigation revealed that a three-electron reduced phenalenyl based triradical aluminum(III) complex plays the key role in such catalysis. The electronic structure of the catalytically active triradical species has been probed using EPR spectroscopy, magnetic susceptibility measurements, and electronic structure calculations using a DFT method.

Erythrosine B Catalyzed Visible-Light Photoredox Arylation–Cyclization of N-Alkyl-N-aryl-2-(trifluoromethyl)acrylamides to 3-(Trifluoromethyl)indolin-2-one Derivatives

3-Trifluoromethylindoline-2-one derivatives were prepared in a visible-light photocatalytic transformation of acrylamides. The arylation–cyclization sequence was initiated by light-induced aryl radical generation from aryldiazonium salts with the utilization of erythrosine B as an organic photocatalyst.

An easy route to (hetero)arylboronic acids

An unprecedented spontaneous reactivity between diazonium salts and diboronic acid has been unveiled, leading to a versatile arylboronic acid synthesis directly from (hetero)arylamines. This fast reaction (35 min overall) tolerates a wide range of functional groups and is carried out under very mild conditions. The radical nature of the reaction mechanism has been investigated.

PREPARATION OF 3,3-DIALKXOY-1-METHYLENEPROPYL ARENES

The invention discloses a method for the preparation of 3,3-dialkxoy-1-methylenepropyl arenes from crotonaldehyde and aryldiazonium salts, and intermediates for the preparation of perfumes.

PREPARATION OF 4,4-DIALKOXY-1-BUTEN-1-YLARENES

The invention discloses a method for the preparation of 4,4-dialkoxy-1-buten-1-ylarenes from crotonaldehyde and aryldiazonium salts, n-buten-1-als and n-butan-1-als derived thereof, their use as fragrances, use of this method in and intermediates for the