4468-57-9

Basic information

• Product Name: 2,3-DIMETHOXYPHENYLACETONITRILE
• Synonyms: 2,3-DIMETHOXYPHENYLACETONITRILE;2-(2,3-dimethoxyphenyl)acetonitrile;2-(2,3-dimethoxyphenyl)ethanenitrile
• CAS NO: 4468-57-9
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.2
• Product Categories: Aromatic Nitriles
• Mol File: 4468-57-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 125°C 1mm
• Flash Point: 109.8°C
• Appearance: /
• Density: 1,13 g/cm3
• Vapor Pressure: 0.00322mmHg at 25°C
• Refractive Index: 1.511
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2,3-DIMETHOXYPHENYLACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIMETHOXYPHENYLACETONITRILE(4468-57-9)
• EPA Substance Registry System: 2,3-DIMETHOXYPHENYLACETONITRILE(4468-57-9)

Safety Data

• Hazard Codes: T
• HazardClass: TOXIC
• Hazardous Substances Data: 4468-57-9(Hazardous Substances Data)

Usage

General Description

2,3-Dimethoxyphenylacetonitrile is a chemical compound with the molecular formula C10H11NO2. It is a white to beige solid that is used as an intermediate in the synthesis of pharmaceuticals and organic compounds. This chemical is commonly used in the production of drugs and agrochemicals, and it is also used as a building block for the synthesis of various other organic compounds. 2,3-Dimethoxyphenylacetonitrile is an important reagent in organic chemistry and is widely used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is important to handle this chemical with care and follow proper safety protocols due to its toxic and hazardous nature.

InChI:InChI=1/C10H11NO2/c1-12-9-5-3-4-8(6-7-11)10(9)13-2/h3-5H,6H2,1-2H3

Upstream product

• 151-50-8 potassium cyanide 
• 3893-01-4 2,3-dimethoxybenzyl chloride 
• 54636-77-0 2,3-dimethoxybenzyl bromide 
• 773837-37-9 sodium cyanide 
• 86-51-1 2,3-dimethyoxybenzaldehyde 
• 5653-67-8 2,3-dimethoxybenzyl alcohol 

Downstream Products

• 858486-97-2 2,4,6-trihydroxy-2',3'-dimethoxy-deoxybenzoin 
• 872306-79-1 2-(2,3-dimethoxy-phenyl)-heptanedinitrile 
• 3494-01-7 (2,3-dimethoxy-phenethyl)-dimethyl-amine 
• 80472-43-1 (E)-2-(2,3-Dimethoxy-phenyl)-3-phenyl-acrylonitrile 
• 83751-77-3 (2,3-Dimethoxy-phenyl)-cyanessigsaeureethylester 
• 132378-47-3 piperonal-(2,3-dimethoxy-phenethylimine) 
• 111355-32-9 (2,3-dimethoxy-phenethyl)-piperonyl-amine 
• 101585-07-3 4-[(2,3-dimethoxy-phenethylimino)-methyl]-phenol 
• 109808-91-5 (2,3-dimethoxy-benzylidene)-(2,3-dimethoxy-phenethyl)-amine 
• 110492-04-1 2-[(2,3-dimethoxy-phenethylimino)-methyl]-6-methoxy-phenol 
• 92301-91-2 2-<2,3-Dimethoxy-phenyl>-isocapronsaeure 
• 92157-47-6 2-(2,3-Dimethoxy-phenyl)-valeriansaeure 
• 92157-18-1 2-(2,3-Dimethoxy-phenyl)-isovaleriansaeure 
• 91555-30-5 2-(2,3-Dimethoxy-phenyl)-buttersaeure 

Relevant articles and documents

PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES

[Problem] A problem is presented in that conventional photochromic compounds cannot be considered adequate in terms of the colorizing/decolorizing rate and durability, and the production process therefore has many steps. The present invention provides an industrially applicable photochromic compound that has both a rapid colorizing/decolorizing reaction and high durability and can also be synthesized at a low cost. [Solution] This compound is characterized in that etheric oxygen atoms are bonded to the carbon atoms at position 1 of a pyranoquinazoline (8H-pyrano[3,2-f]quinazoline) skeleton and position 10 of a naphthopyran (3H-naphtho[2,1-b]pyran) skeleton, said compound having photochromic properties and being a photochromic compound that has both a rapid colorizing/decolorizing reaction and high durability. Also provided is an industrially applicable photochromic compound that can be synthesized at a low cost.

An improved and versatile method for the rapid synthesis of aryldihydrobenzofuran systems by a boron tribromide-mediated cyclization reaction

Boron tribromide is presented as a highly reactive reagent that simultaneously allows the demethylation and fully diastereoselective cyclization of different precursor molecules, obtained by an aldol-type reaction, to a series of hydroxylated aryldihydrobenzofuran systems in racemic form. The latter are often found as key structures in natural compounds of different classes. Syntheses of educts, which mainly took advantage of a versatile Rieche formylation, are also described.

The synthesis of 7,8-dihydroxy-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-1-o1

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