446874-45-9

Upstream product

• 186581-53-3 diazomethane 
• 66543-72-4 3-(3',4',5'-trimethoxyphenyl)propionyl chloride 
• 446874-42-6 4-{6-[3-(tert-butyl-dimethyl-silanyloxy)-5-trimethylsilanyl-pent-4-ynyl]-2,3,4-trimethoxy-phenyl}-4-oxo-butyric acid 
• 446874-41-5 1-[3-(tert-butyl-dimethyl-silanyloxy)-5-trimethylsilanyl-pent-4-ynyl]-2-iodo-3,4,5-trimethoxy-benzene 
• 446874-40-4 5-(2-iodo-3,4,5-trimethoxy-phenyl)-1-trimethylsilanyl-pent-1-yn-3-ol 
• 446874-39-1 3-(2-iodo-3,4,5-trimethoxy-phenyl)-N-methoxy-N-methyl-propionamide 
• 369405-57-2 N-methoxy-N-methyl-3-(3',4',5'-trimethoxyphenyl)propanamide 
• 25173-72-2 3-(3,4,5-trimethoxyphenyl)propanoic acid 
• 446874-43-7 4-{6-[3-(tert-butyl-dimethyl-silanyloxy)-pent-4-ynyl]-2,3,4-trimethoxy-phenyl}-4-oxo-butyric acid 

Relevant academic research and scientific papers

Facile construction of the colchicine skeleton by a rhodium-catalyzed cyclization/cycloaddition cascade

The major alkaloid of the meadow saffron is colchicine, which displays remarkable antimitotic activity and has long been used in the treatment of acute gout and is currently being tested against a broad variety of other diseases. In a remarkable Rh-cataly