447460-30-2Relevant academic research and scientific papers
Triaryl bis-sulfones as cannabinoid-2 receptor ligands: SAR studies
Shankar, Bandarpalle B.,Lavey, Brian J.,Zhou, Guowei,Spitler, James A.,Tong, Ling,Rizvi, Razia,Yang, De-Yi,Wolin, Ronald,Kozlowski, Joseph A.,Shih, Neng-Yang,Wu, Jie,Hipkin, R. William,Gonsiorek, Waldemar,Lunn, Charles A.
, p. 4417 - 4420 (2007/10/03)
We recently reported that compound 1 is a potent inhibitor of the CB2 receptor with high selectivity over CB1. This paper describes the SAR development for this class of compounds. Variation of the substitution pattern on the aromatic rings, as well as th
Cannabinoid receptor ligands
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Page 47, (2008/06/13)
The invention relates to compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmac
