448-60-2

Usage

Uses

Used in Organic Chemistry:
1,3,5-tris(4-fluorophenyl)benzene is used as a unique structural component for the development of new materials due to its rigid and planar nature.
Used in Pharmaceutical Synthesis:
1,3,5-tris(4-fluorophenyl)benzene is used as a valuable intermediate in the synthesis of various pharmaceuticals and organic compounds, contributing to the creation of novel drug molecules.
Used in Organic Electronics and Optoelectronics:
1,3,5-tris(4-fluorophenyl)benzene is used as a subject of interest in the study of organic electronics and optoelectronic materials due to its interesting electronic and photophysical properties.

Upstream product

• 766-98-3 1-ethynyl-4-fluorobenzene 
• 124-38-9 carbon dioxide 

Relevant academic research and scientific papers

Synthesis of α-pyrones by catalytic oxidative coupling of terminal alkynes and carbon dioxide

The use of the complex [(dippe)Ni(μ-H)]2(1) as a catalyst precursor (10?mol%) in the presence of a variety of terminal alkynes and CO2allowed the production of substituted α–pyrones. This reaction occurs using relatively mild conditions (50?°C, 150 psi of CO2) with good to modest yields, depending on the nature of the substituents in the corresponding alkyne. The produced α–pyrones were characterized by different analytical methods and spectroscopic techniques.

The highly selective formation of biaryls by the cyclization of arylethynes catalyzed by vanadyl phthalocyanine

The dimerization of arylethynes catalyzed by vanadium phthalocyanine to give substituted biaryls has been investigated. The reaction yield is always high and for many examples is only slightly affected by the aryl substituents. This fact is also related to the results obtained with metalloporphyrins, which give lower selectivities due to the presence of variable amounts of triphenylbenzenes.

Unusual Products from the Reactions of Anhydrous Hydrogen Chloride with Arylacetylenes

Liquid-phase reactions of anhydrous hydrogen chloride with p-methyl-, p-methoxy-, p-fluoro-, and unsubstituted phenylacetylene afforded cyclic trimers, tetramers, and pentamers of the corresponding arylacetylenes.Phenylacetylene gave additionally 1-methyl-1-phenyl-3-chloroindene.The reactions proceeded via the corresponding HCl diadducts, i.e., via 1-aryl-1,1-dichloroethanes as intermediates.