4481-51-0

Basic information

• Product Name: NSC26194
• Synonyms: NSC26194;2,2'-[Iminobis(methylene)]bis-phenol;2,2'-Dihydroxydibenzylamine;a,a'-Iminodi-o-Cresol;Bis(2-hydroxybenzyl)amine;Bis(o-hydroxybenzylamine);NSC 119557;NSC 407941
• CAS NO: 4481-51-0
• Molecular Formula: C₁₄H₁₅NO₂
• Molecular Weight: 229.2744
• Product Categories: Amines;Aromatics;Amines, Aromatics, Mutagenesis Research Chemicals
• Mol File: 4481-51-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 173-1740C
• Boiling Point: 402.1°Cat760mmHg
• Flash Point: 155.1°C
• Appearance: /
• Density: 1.215g/cm³
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: NSC26194(CAS DataBase Reference)
• NIST Chemistry Reference: NSC26194(4481-51-0)
• EPA Substance Registry System: NSC26194(4481-51-0)

Safety Data

• Hazardous Substances Data: 4481-51-0(Hazardous Substances Data)

Usage

Chemical Properties

Pinkish White Solid

Uses

2,2''-[Iminobis(methylene)]bisphenol (cas# 4481-51-0) is a compound useful in organic synthesis.

Upstream product

• 611-20-1 salicylonitrile 
• 94-67-7 salicylaldehyde-oxime 
• 90-01-7 salicylic alcohol 
• 90-02-8 salicylaldehyde 
• 50-00-0 formaldehyd 
• 108-95-2 phenol 
• 64-17-5 ethanol 
• 26940-74-9 hexamethylenetetramine; compound with phenol 
• 271-95-4 1,2-benzisoxazole 
• 35832-40-7 1,3,5-tris(2-hydroxyphenyl)-2,4-diazapenta-1,4-diene 

Downstream Products

• 42927-80-0 2-(4H-benz[e][1,3]oxazin-3-ylmethyl)-phenol 
• 139662-74-1 spiro-<3,4,5,6-tetrahydro-5-(o-hydroxybenzyl)-2H-1,5-benzoxazocine-3,3'-oxetane> 
• 139662-73-0 spiro-<3,4,5,6-tetrahydro-5-(o-hydroxybenzyl)-2H-1,5-benzoxazocine-3,1'-cyclobutane> 
• 139662-76-3 spiro-<3,4,5,6-tetrahydro-5-(o-hydroxybenzyl)-2H-1,5-benzoxazocine-3,1'-cyclopentane> 
• 139662-77-4 spiro--1,5-dioxa-9-azacyclododecane-3,1'-cyclopentane> 
• 139662-72-9 spiro-<3,4,5,6-tetrahydro-5-(o-hydroxybenzyl)-2H-1,5-benzoxazocine-3,1'-cyclopropane> 
• 177034-90-1 2-([bis(2-hydroxybenzyl)amino]methyl)-6-([bis(2-pyridinylmethyl)amino]methyl)-4-methylphenol 
• 1413932-74-7 C₂₀H₂₃NO₂ 
• 1413932-75-8 N,N-di(2-hydroxybenzyl)formamide 

Relevant articles and documents

On the stereochemistry of the olefinic double bond in 13-membered heterocyclic rings accessible by ring-closing metathesis reaction

13-Membered heterocyclic ring analogs of the core structure of manzamine alkaloids were synthesized by ring closing metathesis (RCM) reaction. The influence of a remote heteroatom (N, O, S) on E/Z stereochemistry of the olefinic double bond formed in RCM reaction using Grubbs 1st and 2nd generation ruthenium carbene complexes was evaluated. Studies show that RCM reaction is kinetically controlled and the hetero atoms influence the double bond stereochemistry.

Method for producing amines by homogeneously catalyzed reductive amination of carbonyl compounds

The invention relates to the preparation of chiral or achiral amines by reaction of aldehydes or ketones with ammonia or primary or secondary amines in the presence of hydrogen and in the presence of homogeneous metal catalysts under mild conditions. Metal catalysts which can be used are complexes of late transition metals with chiral or achiral phosphorus-containing ligands.

One- and Two-Dimensional NMR Study of Resol Phenol-Formaldehyde Prepolymer Resins

A one- and two-dimensional NMR study was performed on three commercial resol phenol-formaldehyde (PF) prepolymer resins. 1H, 13C, CSCM and DQF COSY NMR spectral data, in acetone-d6, were obtained on each resin and on PF model compounds: phenol, five methylolphenols, four diphenylmethanes, two formals, two dibenzyl ethers and two dibenzylamines.Gated-decoupled 13C experiments, using 2,4,6-trimethylphenol as internal standard, were used to quantitate the major components present in each of the three resins.The major chemical differences of the three resins were noted.A DQF COSY method was developed that allowed the qualitative identification of most of the major phenolic components present in each of the PF resins. - Keywords: NMR; 1H NMR; 13C NMR; Phenol-formaldehyde resins