449174-03-2Relevant academic research and scientific papers
Toward the combinatorial synthesis of polyketide libraries: Asymmetric aldol reactions with α-chiral aldehydes on solid support
Paterson, Ian,Temal-Laib, Taoues
, p. 2473 - 2476 (2007/10/03)
(Matrix presented) The viability of performing stereocontrolled aldol additions with α-chiral aldehydes attached by a silyl linker to a hydroxymethylpolystyrene resin is demonstrated for boron and titanium enolates. Subsequent ketone reduction and manipul
