449173-99-3Relevant academic research and scientific papers
Enantioselective preparation of asymmetrically protected 2-propanoyl-1,3-propanediol derivatives: Toward the total synthesis of Kazusamycin A
Arai, Noriyoshi,Chikaraishi, Noriko,Ikawa, Mitsuhiro,Omura, Satoshi,Kuwajima, Isao
, p. 733 - 741 (2007/10/03)
The preparation of enantiomerically pure 2-propanoyl-1,3-propanediol derivatives, key intermediates in our studies on total synthesis of the potent antitumor compound Kazusamycin A are described. After various enzymatic protocols for desymmetrization of t
Toward the combinatorial synthesis of polyketide libraries: Asymmetric aldol reactions with α-chiral aldehydes on solid support
Paterson, Ian,Temal-Laib, Taoues
, p. 2473 - 2476 (2007/10/03)
(Matrix presented) The viability of performing stereocontrolled aldol additions with α-chiral aldehydes attached by a silyl linker to a hydroxymethylpolystyrene resin is demonstrated for boron and titanium enolates. Subsequent ketone reduction and manipul
